Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 7/20 | 0.35 |
| ▸ | MMP1 | P03956 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.31 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.31 |
| ▸ | METAP1 | P53582 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL8824878 | 1.00 | LAP3 (0.40) | LAP3FDPSMMP1MMP2CA2 | |
| SCHEMBL386280 | 0.85 | TSHR (0.44) | TSHR | |
| SCHEMBL8000848 | 0.82 | TSHR (0.41) | TSHR | |
| SCHEMBL8010115 | 0.82 | TSHR (0.41) | TSHR | |
| Phosphine SCHEMBL5568847 | 0.82 | TSHR (0.41) | TSHR | |
| SCHEMBL8824889 | 0.78 | TSHR (0.33) | TSHR | |
| Hypophosphorous Acid SCHEMBL8824894 | 0.78 | TSHR (0.33) | TSHR | |
| Phosphoric Acid SCHEMBL1360058 | 0.76 | LAP3 (0.48) | LAP3FDPSMMP1MMP2CA2 | |
| Phosphoric Acid SCHEMBL8842719 | 0.76 | LAP3 (0.48) | LAP3FDPSMMP1MMP2CA2 | |
| Phosphoric Acid SCHEMBL8842709 | 0.76 | LAP3 (0.48) | LAP3FDPSMMP1MMP2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5695528-A | AGENT COMPRISING WATER SOLUBLE PHOSPHONIUM SALT OF PHOSPHORUS-CONTAINING OXOACID, POLYCARBOXYLIC ACID; FORMALDEHYDE-FREE WASH AND WEAR TREATMENT | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 1997-12-09 | — | — | US | disclosed |