SCHEMBL386280

SCHEMBL386280

CCC(O)P(C(O)CC)C(O)CC

nearest known ligand 0.44

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphine SCHEMBL5568847 0.96 TSHR (0.41) TSHR
SCHEMBL8000848 0.96 TSHR (0.41) TSHR
SCHEMBL8010115 0.96 TSHR (0.41) TSHR
Phosphoric Acid SCHEMBL8824878 0.85 LAP3 (0.40) TSHR
Phosphoric Acid SCHEMBL8824868 0.85 LAP3 (0.40) TSHR
Hypophosphorous Acid SCHEMBL8824894 0.85 TSHR (0.33) TSHR
SCHEMBL8824889 0.85 TSHR (0.33) TSHR
SCHEMBL14840308 0.83 TSHR (0.44) TSHR
SCHEMBL11045121 0.81 TSHR (0.42) TSHR
Acetic Acid SCHEMBL8010204 0.81 CA1 (0.40) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4748941-A2 NUCLEOSIDES AND NUCLEOTIDES WITH 3 -HYDROXY BLOCKING GROUPS Illumina Cambridge Limited (GB) 2026-05-27 EP claimed
EP-3902814-B1 NUCLEOSIDES AND NUCLEOTIDES WITH 3'-HYDROXY BLOCKING GROUPS AND THEIR USE IN POLYNUCLEOTIDE SEQUENCING METHODS ILLUMINA CAMBRIDGE LTD (GB) 2026-04-08 EP claimed
US-12595508-B2 Nucleotide cleavable linkers and uses thereof Singular Genomics Systems, Inc. (US) 2026-04-07 US claimed
US-20250387789-A1 FLOW CELLS ILLUMINA INC (US) 2025-12-25 US claimed
EP-4652176-A1 METHODS OF OBTAINING KERATIN PROTEIN ISOLATE, KERATIN AMYLOID FIBRILS AND FABRICATING MEMBRANES USING THE SAME Nanyang Technological University (SG) 2025-11-26 EP claimed
EP-4642931-A1 METHODS OF SEQUENCING USING 3´ ALLYL BLOCKED NUCLEOTIDES Illumina, Inc. (US) 2025-11-05 EP claimed
EP-4638794-A1 PALLADIUM CATALYST COMPOSITIONS AND METHODS FOR SEQUENCING BY SYNTHESIS Illumina, Inc. (US) 2025-10-29 EP claimed
US-12409449-B2 Flow cells ILLUMINA, INC. (US) 2025-09-09 US claimed
WO-2025137528-A1 REDUCING AGENT COMPOSITIONS FOR ISOTHERMAL AMPLIFICATION OF NUCLEIC ACIDS ABBOTT LABORATORIES (US) 2025-06-26 WO claimed
WO-2025132825-A1 1H-IMIDAZO[4,5-C]QUINOLINE METAL-BASED COMPLEXES USEFUL AS MEDICAMENTS FUNDACIÓN DONOSTIA INTERNATIONAL PHYSICS CENTER - DIPC (ES) 2025-06-26 WO claimed
WO-2006089395-A1 NEAR-NEUTRAL DEINKING OF RECYCLED PULP USING PHOSPHINES OR PHOSPHONIUM SALTS FPINNOVATIONS (CA) 2006-08-31 WO claimed
EP-1651704-A1 COATING COMPOSITIONS CONTAINING AMINOFUNCTIONAL SILICONE RESINS Dow Corning Corporation (US) 2006-05-03 EP claimed
EP-1598053-A1 Use of a composition containing at least one phosphine as majority reducing agent to remove the artificial colour of keratinic fibres L'OREAL (FR) 2005-11-23 EP claimed
US-20050251928-A1 Method for stripping artificial color from keratin fibers L'OREAL (FR) 2005-11-17 US claimed
US-20050176093-A1 SELECTIVE LABELING AGENT FOR PHOSPHOPROTEOME ANALYSIS AND PHOSPHORYLATED SITE ANALYSIS KOREA BASIC SCIENCE INSTITUTE (KR) 2005-08-11 US claimed
WO-2005010078-A1 COATING COMPOSITIONS CONTAINING AMINOFUNCTIONAL SILICONE RESINS DOW CORNING CORPORATION (US) 2005-02-03 WO claimed
WO-2004101597-A2 METHODS FOR THE REDUCTION OF DISULFIDE BONDS FRUTAROM LTD. (IL) 2004-11-25 WO claimed
US-6084113-A REACTING A DIENE WITH A TELOMER, E.G., AMMONIA, WATER, TO OBTAIN A BUTADIENAMINE OR ALCOHOL; CATALYST SELECTIVITY; PURITY; EASY SEPARATION OF WATER-SOLUBLE CATALYST BAYER AKTIENGESELLSCHAFT (DE) 2000-07-04 US claimed
EP-0816308-A1 Complexes containing tris(hydroxyalkyl)phosphines for telomerisations ans as catalysts BAYER AG (DE) 1998-01-07 EP claimed
US-5147409-A Shrinkage and pulling resistance; improved bleaching, dyeing NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) 1992-09-15 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12595508-B2 Nucleotide cleavable linkers and uses thereof NSUN2, CCRL2, NOP2 TSHR 87/4885
US-20250387789-A1 FLOW CELLS SMCHD1, PCNA, RAD1 TSHR 1478/4885
US-20050251928-A1 Method for stripping artificial color from keratin fibers KRT18, DSG1, JUP TSHR 4245/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.