Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | AGXT | P21549 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5572222 | 0.84 | SSTR4 (0.41) | TAAR1OPRL1OPRM1SLC6A3SLC6A2 | |
| SCHEMBL208130 | 0.83 | AOC3 (0.44) | TAAR1OPRL1OPRM1SLC6A3SLC6A2 | |
| SCHEMBL5290991 | 0.83 | KMT2A (0.43) | TAAR1OPRL1OPRM1MEN1KMT2A | |
| SCHEMBL4118593 | 0.82 | AQP1 (0.41) | TAAR1OPRL1OPRM1SLC6A3SLC6A2 | |
| SCHEMBL205961 | 0.82 | OPRL1 (0.57) | OPRL1OPRM1KDM1AOPRK1 | |
| SCHEMBL3216894 | 0.78 | TAAR1 (0.44) | TAAR1OPRL1OPRM1SLC6A3SLC6A2 | |
| SCHEMBL5392050 | 0.77 | OPRM1 (0.51) | OPRL1OPRM1OPRK1IDO1AGXT | |
| SCHEMBL5381826 | 0.77 | OPRM1 (0.51) | OPRL1OPRM1OPRK1IDO1AGXT | |
| SCHEMBL3218498 | 0.76 | TAAR1 (0.42) | TAAR1OPRL1OPRM1SLC6A3SLC6A2 | |
| SCHEMBL3219971 | 0.75 | OPRL1 (0.51) | TAAR1OPRL1OPRM1SLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070129369-A1 | Heteroaryl substituted cyclohexyl-1,4-diamine compounds | GRUENENTHAL GMBH (DE) | 2007-06-07 | — | — | US | claimed |
| US-20070129369-A1 | Heteroaryl substituted cyclohexyl-1,4-diamine compounds | GRUENENTHAL GMBH (DE) | 2007-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129369-A1 | Heteroaryl substituted cyclohexyl-1,4-diamine compounds | DDC, DPYD, PKD1 | TAAR1 2781/4885OPRL1 2457/4885OPRM1 2315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.