Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7219075 | 0.85 | NLRP3 (0.55) | NLRP3ALDH1A1GAAL3MBTL1MAPT | |
| SCHEMBL23218359 | 0.84 | NLRP3 (0.48) | NLRP3ALDH1A1GAAL3MBTL1MAPT | |
| SCHEMBL30676655 | 0.84 | NLRP3 (0.48) | NLRP3ALDH1A1GAAL3MBTL1MAPT | |
| SCHEMBL29122112 | 0.81 | NLRP3 (0.48) | NLRP3ALDH1A1GAAL3MBTL1MAPT | |
| SCHEMBL7790350 | 0.79 | GABRA1 (0.41) | ALDH1A1MAPTTSHR | |
| SCHEMBL29853048 | 0.76 | NLRP3 (0.44) | NLRP3ALDH1A1GAAL3MBTL1MAPT | |
| SCHEMBL23219226 | 0.76 | NLRP3 (0.44) | NLRP3ALDH1A1GAAL3MBTL1MAPT | |
| SCHEMBL2135611 | 0.75 | NLRP3 (0.43) | NLRP3ALDH1A1GAAL3MBTL1MAPT | |
| SCHEMBL2135834 | 0.75 | CYP4F2 (0.50) | NLRP3ALDH1A1GAAL3MBTL1MAPT | |
| SCHEMBL16884620 | 0.75 | GABRA1 (0.38) | ALDH1A1MAPTCYP2C9KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169890-B2 | Process for the production of ramoplanin-like amide derivatives | VICURON PHARMACEUTICALS INC. (US) | 2007-01-30 | — | — | US | disclosed |
| US-20050106691-A1 | Process for the production of ramoplanin-like amide derivatives | VICURON PHARMACEUTICALS INC. (US) | 2005-05-19 | — | — | US | disclosed |