Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 18/20 | 0.77 |
| ▸ | EGFR | P00533 | 7/20 | 0.71 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.68 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.68 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.68 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.68 |
| ▸ | AURKA | O14965 | 1/20 | 0.64 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.64 |
| ▸ | GAK | O14976 | 1/20 | 0.63 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.63 |
| ▸ | STK10 | O94804 | 1/20 | 0.63 |
| ▸ | RET | P07949 | 1/20 | 0.63 |
| ▸ | FLT3 | P36888 | 1/20 | 0.63 |
| ▸ | JAK3 | P52333 | 1/20 | 0.63 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.63 |
| ▸ | Q6ZSR9 | Q6ZSR9 | 1/20 | 0.63 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.63 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.63 |
| ▸ | RPS6KA6 | Q9UK32 | 1/20 | 0.63 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5565237 | 0.91 | EGFR (0.67) | KDREGFRRET | |
| SCHEMBL31067650 | 0.80 | KDR (0.83) | KDREGFRAURKAAURKB | |
| SCHEMBL31067666 | 0.80 | KDR (1.00) | KDREGFRAURKAAURKB | |
| SCHEMBL31067640 | 0.80 | KDR (0.84) | KDREGFRAURKAAURKBGAK | |
| SCHEMBL31067662 | 0.79 | EGFR (0.82) | KDREGFRAURKAAURKB | |
| SCHEMBL31067708 | 0.79 | KDR (0.82) | KDREGFRAURKAAURKBGAK | |
| SCHEMBL31067633 | 0.79 | KDR (0.82) | KDREGFRAURKAAURKB | |
| SCHEMBL12069005 | 0.79 | SRC (0.82) | KDREGFRAURKAAURKBGAK | |
| SCHEMBL5473733 | 0.78 | KDR (0.74) | KDREGFRAURKAAURKBGAK | |
| SCHEMBL6026878 | 0.78 | KDR (0.63) | KDREGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070123537-A1 | Quinazoline derivatives for the treatment of herpesviral infections | GPC BIOTECH AG (DE) | 2007-05-31 | — | — | US | claimed |
| US-20070123537-A1 | Quinazoline derivatives for the treatment of herpesviral infections | GPC BIOTECH AG (DE) | 2007-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070123537-A1 | Quinazoline derivatives for the treatment of herpesviral infections | IRF3, PML, TPMT | KDR 2712/4885EGFR 1445/4885PIK3CD 978/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.