SCHEMBL5569284

SCHEMBL5569284

C[Si](c1ccccc1)(C(F)F)C(F)(F)F

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 3/20 0.40
NR1H3 Q13133 3/20 0.40
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL104796 0.72 NR1H2 (0.45) NR1H2NR1H3ESR1ESR2ALDH1A1
SCHEMBL29054459 0.72 NR1H2 (0.45) NR1H2NR1H3ESR1ESR2ALDH1A1
SCHEMBL3271165 0.72 ESR1 (0.39) NR1H2NR1H3ESR1ESR2TSHR
SCHEMBL3160992 0.71 NR1H2 (0.33) NR1H2NR1H3ESR1ESR2ALDH1A1
SCHEMBL4642449 0.70 NR1H2 (0.32) NR1H2NR1H3ESR1ESR2ALDH1A1
SCHEMBL3481533 0.69 NR1H2 (0.37) NR1H2NR1H3ESR1ESR2TSHR
SCHEMBL24433593 0.68 NR1H2 (0.42) NR1H2NR1H3ESR1ESR2ALDH1A1
SCHEMBL23701389 0.67 ALDH1A1 (0.38) NR1H2NR1H3ESR1ESR2ALDH1A1
SCHEMBL28893523 0.67 ESR1 (0.39) NR1H2NR1H3ESR1ESR2ALDH1A1
SCHEMBL1051334 0.66 ALDH1A1 (0.41) NR1H2NR1H3ESR1ESR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1623264-B1 SWITCHABLE OPTICAL ELEMENT USING SURFACTANTS KONINKL PHILIPS NV (NL) 2015-11-04 EP claimed
US-7251392-B2 Reduction of driving voltage in a switchable element KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2007-07-31 US claimed
US-20060215273-A1 Reduction of driving voltage in a switchable element KONINKLIJKE PHILIPS ELECTRONICS N.V. 2006-09-28 US claimed
EP-1623264-A1 REDUCTION OF DRIVING VOLTAGE IN A SWITCHABLE ELEMENT Koninklijke Philips Electronics N.V. (NL) 2006-02-08 EP claimed
WO-2004099846-A1 REDUCTION OF DRIVING VOLTAGE IN A SWITCHABLE ELEMENT KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2004-11-18 WO claimed
EP-3352887-B1 METHOD OF REMOVING VOLATILE COMPOUNDS FOR EMULSIONS DOW SILICONES CORP (US) 2024-09-04 EP disclosed
CN-108136334-B Method for removing volatile compounds from emulsions 美国陶氏有机硅公司 2021-09-21 CN disclosed
EP-3473328-A1 METHOD OF SEPARATING VOLATILE SILOXANE FROM A LIQUID FEED MIXTURE Dow Silicones Corporation (US) 2019-04-24 EP disclosed
EP-3122440-B1 METHOD OF SEPARATING VOLATILE SILOXANE FROM A LIQUID FEED MIXTURE DOW SILICONES CORP (US) 2018-11-21 EP disclosed
EP-3352887-A1 METHOD OF REMOVING VOLATILE COMPOUNDS FOR EMULSIONS Dow Silicones Corporation (US) 2018-08-01 EP disclosed
US-20180200675-A1 METHOD OF REMOVING VOLATILE COMPOUNDS FROM EMULSIONS DOW SILICONES CORPORATION 2018-07-19 US disclosed
US-9962657-B2 Method of and system for separating volatile siloxane from feed mixture DOW CORNING CORPORATION (US) 2018-05-08 US disclosed
WO-2004099846-A1 REDUCTION OF DRIVING VOLTAGE IN A SWITCHABLE ELEMENT KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2004-11-18 WO disclosed
EP-1396040-A2 ADDITIVE FOR LITHIUM-ION BATTERY E.I. Dupont de Nemours and Company, Inc. (US) 2004-03-10 EP disclosed
WO-2004012691-A1 USE OF SILANES IN COSMETIC AGENTS AND METHODS FOR TREATING HAIR ITN NANOVATION GMBH (DE) 2004-02-12 WO disclosed
WO-2002080291-A2 ADDITIVE FOR LITHIUM-ION BATTERY E.I. DUPONT DE NEMOURS AND COMPANY (US) 2002-10-10 WO disclosed
US-20020110735-A1 Additive for lithium-ion battery E.I. DU PONT DE NEMOURS AND COMPANY 2002-08-15 US disclosed
EP-0330058-B1 PROCESS FOR THE PREPARATION OF SILYLETHER AND ALCOHOLS HAVING A PERFLUOROALKYL REST HOECHST AKTIENGESELLSCHAFT (DE) 1991-10-02 EP disclosed
US-4968848-A Process of the prparation of perfluoroalkyl compounds, and pentafluoroethyltrimethylsilane HOECHST AKTIENGESELLSCHAFT (DE) 1990-11-06 US disclosed
EP-0330058-A1 Process for the preparation of silylether and alcohols having a perfluoroalkyl rest HOECHST AKTIENGESELLSCHAFT (DE) 1989-08-30 EP disclosed