Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 16/20 | 0.85 |
| ▸ | CTSL | P07711 | 15/20 | 0.85 |
| ▸ | CTSK | P43235 | 7/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3595483 | 0.77 | CTSS (0.69) | CTSSCTSLCTSK | |
| SCHEMBL3586488 | 0.66 | CTSS (0.68) | CTSSCTSLCTSK | |
| SCHEMBL5571480 | 0.66 | CTSL (0.58) | CTSSCTSLCTSK | |
| SCHEMBL3605083 | 0.65 | CTSL (0.81) | CTSSCTSLCTSK | |
| SCHEMBL3593711 | 0.65 | CTSL (1.00) | CTSSCTSLCTSK | |
| SCHEMBL3589178 | 0.64 | CTSS (0.58) | CTSSCTSLCTSK | |
| SCHEMBL3586215 | 0.64 | CTSS (0.51) | CTSSCTSLCTSK | |
| SCHEMBL5567274 | 0.62 | CTSL (0.85) | CTSSCTSLCTSK | |
| SCHEMBL3596145 | 0.62 | CTSS (0.52) | CTSSCTSLCTSK | |
| SCHEMBL5572278 | 0.60 | CTSL (0.72) | CTSSCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781623-A1 | COMPOUNDS AND COMPOSITIONS USEFUL AS CATHEPSIN S INHIBITORS | Novartis AG (CH) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006018284-A1 | COMPOUNDS AND COMPOSITIONS USEFUL AS CATHEPSIN S INHIBITORS | NOVARTIS AG (CH) | 2006-02-23 | — | — | WO | disclosed |