SCHEMBL472804

SCHEMBL472804

O=c1sc2nc3cc4ccccc4cc3nc2s1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.58
NQO2 P16083 1/20 0.50
RPS6KB2 Q9UBS0 5/20 0.42
ALDH1A1 P00352 5/20 0.38
MAPT P10636 4/20 0.38
HPGD P15428 3/20 0.38
KDM4E B2RXH2 2/20 0.38
GLA P06280 2/20 0.38
GAA P10253 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
ELANE P08246 1/20 0.38
NPC1 O15118 1/20 0.38
USP2 O75604 1/20 0.38
RAB9A P51151 1/20 0.38
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
POLB P06746 2/20 0.36
ACHE P22303 1/20 0.36
GRIN2D O15399 1/20 0.35
GRIN3B O60391 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL556965 0.84 TDP1 (0.59) TDP1NQO2ALDH1A1MAPTHPGD
Chinomethionat SCHEMBL29358969 0.74 TDP1 (1.00) TDP1NQO2ALDH1A1MAPTKDM4E
SCHEMBL13156487 0.72 NQO2 (0.88) TDP1NQO2RPS6KB2ALDH1A1MAPT
SCHEMBL472209 0.69 NQO2 (0.62) TDP1NQO2RPS6KB2ALDH1A1MAPT
SCHEMBL25879665 0.68 NQO2 (0.54) TDP1NQO2RPS6KB2ALDH1A1MAPT
SCHEMBL2247546 0.68 NQO2 (0.68) TDP1NQO2RPS6KB2ALDH1A1MAPT
Benzo[B]Phenazine SCHEMBL5481172 0.68 NQO2 (1.00) TDP1NQO2RPS6KB2ALDH1A1MAPT
SCHEMBL31319857 0.66 NQO2 (0.94) TDP1NQO2RPS6KB2ALDH1A1MAPT
SCHEMBL7695642 0.64 ALDH1A1 (0.65) TDP1NQO2RPS6KB2ALDH1A1MAPT
SCHEMBL18397673 0.64 NQO2 (0.62) TDP1NQO2RPS6KB2ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8530673-B2 Tetrathiafulvalene derivative, and organic film and organic transistor using the same RICOH COMPANY, LTD. (JP) 2013-09-10 US disclosed
EP-2411378-B1 TETRATHIAFULVALENE DERIVATIVE, AND ORGANIC FILM AND ORGANIC TRANSISTOR USING THE SAME RICOH CO LTD (JP) 2012-12-19 EP disclosed
EP-2411378-B1 TETRATHIAFULVALENE DERIVATIVE, AND ORGANIC FILM AND ORGANIC TRANSISTOR USING THE SAME RICOH CO LTD (JP) 2012-12-19 EP disclosed
US-20120035364-A1 TETRATHIAFULVALENE DERIVATIVE, AND ORGANIC FILM AND ORGANIC TRANSISTOR USING THE SAME RICOH COMPANY, LTD. (JP) 2012-02-09 US disclosed
US-20120035364-A1 TETRATHIAFULVALENE DERIVATIVE, AND ORGANIC FILM AND ORGANIC TRANSISTOR USING THE SAME RICOH COMPANY, LTD. (JP) 2012-02-09 US disclosed
US-20120035364-A1 TETRATHIAFULVALENE DERIVATIVE, AND ORGANIC FILM AND ORGANIC TRANSISTOR USING THE SAME RICOH COMPANY, LTD. (JP) 2012-02-09 US disclosed
EP-2411378-A1 TETRATHIAFULVALENE DERIVATIVE, AND ORGANIC FILM AND ORGANIC TRANSISTOR USING THE SAME Ricoh Company, Ltd. (JP) 2012-02-01 EP disclosed
WO-2010110351-A1 TETRATHIAFULVALENE DERIVATIVE, AND ORGANIC FILM AND ORGANIC TRANSISTOR USING THE SAME RICOH COMPANY, LTD. (JP) 2010-09-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120035364-A1 TETRATHIAFULVALENE DERIVATIVE, AND ORGANIC FILM AND ORGANIC TRANSISTOR USING THE SAME TCOF1, F12, F5 TDP1 711/4885NQO2 3118/4885RPS6KB2 3321/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.