Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18485469 | 0.88 | LMNA (0.40) | KMT2ALMNANPSR1ATMALDH1A1 | |
| SCHEMBL18485387 | 0.82 | ALDH1A1 (0.61) | KMT2ALMNAALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL18485465 | 0.81 | GAA (0.47) | KMT2ALMNANPSR1ATMALDH1A1 | |
| SCHEMBL11583929 | 0.81 | KMT2A (0.33) | KMT2AATMALDH1A1TSHRL3MBTL1 | |
| SCHEMBL6930133 | 0.80 | TSHR (0.37) | LMNANPSR1ATMALDH1A1TSHR | |
| SCHEMBL18485421 | 0.80 | KMT2A (0.45) | KMT2ALMNAATMALDH1A1TSHR | |
| SCHEMBL18485466 | 0.78 | LMNA (0.45) | KMT2ALMNANPSR1ATMALDH1A1 | |
| SCHEMBL6831925 | 0.77 | BCHE (0.41) | KMT2ALMNANPSR1ALDH1A1TSHR | |
| SCHEMBL18485452 | 0.75 | LMNA (0.42) | KMT2ALMNANPSR1ATMALDH1A1 | |
| SCHEMBL13169805 | 0.75 | CA9 (0.44) | KMT2ALMNANPSR1ATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170114339-A1 | Inactivation Method | THERMO FISHER SCIENTIFIC BALTICS UAB (LT) | 2017-04-27 | — | — | US | claimed |
| EP-1806400-B1 | Inactivation method | FERMENTAS UAB (LT) | 2013-03-13 | — | — | EP | claimed |
| US-20070224611-A1 | Inactivation method | FERMENTAS UAB | 2007-09-27 | — | — | US | claimed |
| EP-1806400-A2 | Inactivation method | Fermentas UAB (LT) | 2007-07-11 | — | — | EP | claimed |
| EP-3186374-A1 | REVERSIBLY INACTIVATED THERMOSTABLE REVERSE TRANSCRIPTASES, COMPOSITIONS AND METHODS FOR USE | Life Technologies Corporation (US) | 2017-07-05 | — | — | EP | disclosed |
| US-20170117588-A1 | ADDITIVE FOR NON-AQUEOUS ELECTROLYTE, NON-AQUEOUS ELECTROLYTE, AND POWER STORAGE DEVICE | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2017-04-27 | — | — | US | disclosed |
| US-20170117588-A1 | ADDITIVE FOR NON-AQUEOUS ELECTROLYTE, NON-AQUEOUS ELECTROLYTE, AND POWER STORAGE DEVICE | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2017-04-27 | — | — | US | disclosed |
| US-20170117588-A1 | ADDITIVE FOR NON-AQUEOUS ELECTROLYTE, NON-AQUEOUS ELECTROLYTE, AND POWER STORAGE DEVICE | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2017-04-27 | — | — | US | disclosed |
| US-20170114339-A1 | Inactivation Method | THERMO FISHER SCIENTIFIC BALTICS UAB (LT) | 2017-04-27 | — | — | US | disclosed |
| EP-3131153-A1 | ADDITIVE FOR NON-AQUEOUS ELECTROLYTE, NON-AQUEOUS ELECTROLYTE, AND POWER STORAGE DEVICE | Sumitomo Seika Chemicals Co., Ltd. (JP) | 2017-02-15 | — | — | EP | disclosed |
| EP-3131153-A1 | ADDITIVE FOR NON-AQUEOUS ELECTROLYTE, NON-AQUEOUS ELECTROLYTE, AND POWER STORAGE DEVICE | Sumitomo Seika Chemicals Co., Ltd. (JP) | 2017-02-15 | — | — | EP | disclosed |
| US-20160264950-A1 | REVERSIBLY INACTIVATED THERMOSTABLE REVERSE TRANSCRIPTASES, COMPOSITIONS AND METHODS FOR USE | Life Technologies Corporation | 2016-09-15 | — | — | US | disclosed |
| WO-2016033116-A1 | REVERSIBLY INACTIVATED THERMOSTABLE REVERSE TRANSCRIPTASES, COMPOSITIONS AND METHODS FOR USE | Life Technologies Corporation (US) | 2016-03-03 | — | — | WO | disclosed |
| US-9273304-B2 | Inactivation method | THERMO FISHER SCIENTIFIC BALTICS UAB (LT) | 2016-03-01 | — | — | US | disclosed |
| EP-1806400-B1 | Inactivation method | FERMENTAS UAB (LT) | 2013-03-13 | — | — | EP | disclosed |
| US-20070224611-A1 | Inactivation method | FERMENTAS UAB | 2007-09-27 | — | — | US | disclosed |
| EP-1806400-A2 | Inactivation method | Fermentas UAB (LT) | 2007-07-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070224611-A1 | Inactivation method | TREH, UNG, NOTUM | KMT2A 1982/4885LMNA 3330/4885NPSR1 4190/4885 |
| US-20170114339-A1 | Inactivation Method | TREH, UNG, NOTUM | KMT2A 1982/4885LMNA 3330/4885NPSR1 4190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.