Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 3/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | APEX1 | P27695 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7146924 | 0.81 | NFKB1 (0.64) | NFKB1SMN1; SMN2BLMPMP22MAPT | |
| SCHEMBL2065519 | 0.81 | NFKB1 (0.64) | NFKB1SMN1; SMN2BLMPMP22MAPT | |
| SCHEMBL27898486 | 0.81 | NFKB1 (0.64) | NFKB1SMN1; SMN2BLMPMP22MAPT | |
| Hydrochloric Acid SCHEMBL2065125 | 0.80 | BLM (0.65) | NFKB1SMN1; SMN2BLMPMP22MAPT | |
| Hydrochloric Acid SCHEMBL6760975 | 0.80 | BLM (0.65) | NFKB1SMN1; SMN2BLMPMP22MAPT | |
| SCHEMBL12356908 | 0.80 | CSNK2A1 (0.57) | CSNK2A1GLASMN1; SMN2MAPTMEN1 | |
| SCHEMBL5569665 | 0.79 | CSNK2A1 (0.58) | CSNK2A1NFKB1BLMPMP22MAPT | |
| SCHEMBL16959180 | 0.77 | CSNK2A1 (0.54) | CSNK2A1GLASMN1; SMN2MAPTMEN1 | |
| SCHEMBL7914446 | 0.75 | NFKB1 (0.60) | NFKB1BLMPMP22ADRA2AADRA1A | |
| SCHEMBL25101010 | 0.74 | TAAR1 (0.50) | NFKB1SMN1; SMN2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070219192-A1 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INCORPORATED | 2007-09-20 | — | — | US | claimed |
| US-20070219192-A1 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INCORPORATED | 2007-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219192-A1 | Certain chemical entities, compositions, and methods | KIF5B, KIF2C, PLK1 | CSNK2A1 401/4885NFKB1 3201/4885GLA 2181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.