Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.33 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | AGER | Q15109 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | PTPRC | P08575 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4443108 | 0.95 | SMN1; SMN2 (0.34) | SMN1; SMN2HPGDRAB9ANPC1TP53 | |
| SCHEMBL8149220 | 0.91 | ROCK2 (0.36) | SMN1; SMN2HPGDTSHRROCK2ABCB1 | |
| SCHEMBL4444992 | 0.90 | SMN1; SMN2 (0.38) | SMN1; SMN2HPGDRAB9ANPC1TP53 | |
| SCHEMBL28439942 | 0.88 | HTR7 (0.40) | SMN1; SMN2HPGDRAB9ANPC1TP53 | |
| SCHEMBL20304 | 0.88 | HTR7 (0.40) | SMN1; SMN2HPGDRAB9ANPC1TP53 | |
| SCHEMBL30068977 | 0.87 | HTR7 (0.39) | SMN1; SMN2HPGDRAB9ANPC1TP53 | |
| SCHEMBL5502813 | 0.87 | HTR7 (0.39) | SMN1; SMN2HPGDRAB9ANPC1TP53 | |
| SCHEMBL4216711 | 0.87 | HTR7 (0.39) | SMN1; SMN2HPGDRAB9ANPC1TP53 | |
| Hydrochloric Acid SCHEMBL29391428 | 0.87 | HTR7 (0.39) | SMN1; SMN2HPGDRAB9ANPC1TP53 | |
| SCHEMBL30181989 | 0.87 | HTR7 (0.39) | SMN1; SMN2HPGDRAB9ANPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761548-A1 | PROCESS FOR THE PREPARATION OF ASYMMETRICALLY SUBSTITUTED BIARYLDIPHOSPHINES | LONZA AG (CH) | 2007-03-14 | — | — | EP | disclosed |
| WO-2006002729-A1 | PROCESS FOR THE PREPARATION OF ASYMMETRICALLY SUBSTITUTED BIARYLDIPHOSPHINES | LONZA AG (CH) | 2006-01-12 | — | — | WO | disclosed |
| EP-1609795-A1 | Process for the preparation of asymmetrically substituted biaryldiphosphines | Lonza AG (CH) | 2005-12-28 | — | — | EP | disclosed |