SCHEMBL5569934

SCHEMBL5569934

Cc1cccc(-c2nc(-c3ccc(O)cc3O)nc(-c3cccc(C)c3C)n2)c1C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.49
MGAM O43451 2/20 0.49
SI P14410 2/20 0.49
MGAM2 Q2M2H8 2/20 0.49
TRPA1 O75762 1/20 0.42
ATM Q13315 1/20 0.42
TLR8 Q9NR97 1/20 0.41
KMT2A Q03164 3/20 0.41
MAPK1 P28482 3/20 0.40
KDM4E B2RXH2 3/20 0.40
MEN1 O00255 2/20 0.40
LMNA P02545 2/20 0.40
MAPT P10636 1/20 0.40
HTT P42858 1/20 0.40
CHEK1 O14757 1/20 0.40
WEE1 P30291 1/20 0.40
HSD17B10 Q99714 4/20 0.40
ANPEP P15144 1/20 0.40
DPP4 P27487 1/20 0.40
ESR2 Q92731 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5703467 1.00 GAA (0.49) GAAMGAMSIMGAM2TRPA1
SCHEMBL5703420 0.89 TLR8 (0.43) GAAMGAMSIMGAM2TLR8
SCHEMBL1245326 0.86 HSD17B10 (0.50) GAAMGAMSIMGAM2ATM
SCHEMBL2860157 0.84 TRPA1 (0.50) GAAMGAMSIMGAM2TRPA1
SCHEMBL1244598 0.82 NUDT1 (0.43) GAATRPA1ATMTLR8MAPK1
SCHEMBL28961586 0.80 CYP3A4 (0.48) GAAMGAMSIMGAM2KMT2A
SCHEMBL547889 0.80 NPC1 (0.52) GAAKDM4EMAPTHTTESR2
SCHEMBL29625130 0.80 NPC1 (0.52) GAAKDM4EMAPTHTTESR2
SCHEMBL14070316 0.78 HSD17B10 (0.50) GAAMGAMSIMGAM2KMT2A
SCHEMBL18913903 0.78 SMN1; SMN2 (0.57) GAAKMT2AMAPK1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1769025-A1 POROUS INORGANIC MATERIALS CONTAINING POLYMER ADDITIVES Ciba SC Holding AG (CH) 2007-04-04 EP disclosed
EP-1170290-B1 Compounds having ultra-violet absorption properties CIBA SC HOLDING AG (CH) 2006-06-07 EP disclosed
WO-2006008240-A1 POROUS INORGANIC MATERIALS CONTAINING POLYMER ADDITIVES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-01-26 WO disclosed
EP-1109792-B1 PROCESS FOR MAKING 2- (2,4- DIHYDROXYPHENYL) OR 2- (2,4- DIALKOXYPHENYL)- 4,6- BISARYL- 1,3,5- TRIAZINES CYTEC TECH CORP (US) 2005-07-27 EP disclosed
EP-1382599-A2 2-(2,4 dihydroxyphenyl)-4,6 bis(3,4-dimethylphenyl)-s-triazine and 2-(2,4-dihydroxyphenyl)4(3,4-dimethylphenyl)-6-(2,3-dimethylphenyl)-s-triazine and derivatives thereof as UV-absorber CYTEC TECHNOLOGY CORP. (US) 2004-01-21 EP disclosed
EP-0693483-B1 Compounds having ultra-violet absorption properties CIBA SC HOLDING AG (CH) 2002-04-10 EP disclosed
EP-1170290-A2 Compounds having ultra-violet absorption properties Ciba SC Holding AG (CH) 2002-01-09 EP disclosed
EP-1109792-A1 PROCESS FOR MAKING 2- (2,4- DIHYDROXYPHENYL) OR 2- (2,4- DIALKOXYPHENYL)- 4,6- BISARYL- 1,3,5- TRIAZINES CYTEC TECHNOLOGY CORP. (US) 2001-06-27 EP disclosed
US-6225468-B1 HEATING AND PRESSURIZING TRIHALO-1,3,5-TRIAZINE WITH PHENOL DERIVATIVE AND BENZENE DERIVATIVE TO IN PRESENCE OF CATALYST FORM ARYL SUBSTITUTED TRIAZINE COMPOUND CYTEC TECHNOLOGY CORP. 2001-05-01 US disclosed
US-6045586-A IMPROVING THE SUN PROTECTION FACTOR (SPF) OF TEXTILE FIBRE BY TREATING WITH 1,3,5-TRIAZINE DERIVATIVES OF GIVEN FORMULA CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-04-04 US disclosed
WO-2000014077-A1 PROCESS FOR MAKING 2- (2,4- DIHYDROXYPHENYL) OR 2- (2,4- DIALKOXYPHENYL)- 4,6- BISARYL- 1,3,5- TRIAZINES CYTEC TECHNOLOGY CORP. (US) 2000-03-16 WO disclosed
US-5543518-A ALKYLATION OF TRIS-ARYL-S-TRIAZINE COMPOUNDS WITH ALKENES, CYCLOALKENES, PHENYLALKENES CIBA-GEIGY CORPORATION (US) 1996-08-06 US disclosed
EP-0693483-A1 Compounds having ultra-violet absorption properties CIBA-GEIGY AG (CH) 1996-01-24 EP disclosed