Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 2/20 | 0.51 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.51 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 2/20 | 0.48 |
| ▸ | MMP8 | P22894 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1487164 | 1.00 | SLC1A3 (0.51) | SLC1A3SLC1A2SLC1A1KMT2ACYP1A2 | |
| SCHEMBL1362199 | 1.00 | SLC1A3 (0.51) | SLC1A3SLC1A2SLC1A1KMT2ACYP1A2 | |
| SCHEMBL1362196 | 1.00 | SLC1A3 (0.51) | SLC1A3SLC1A2SLC1A1KMT2ACYP1A2 | |
| SCHEMBL1362201 | 1.00 | SLC1A3 (0.51) | SLC1A3SLC1A2SLC1A1KMT2ACYP1A2 | |
| SCHEMBL21843005 | 0.86 | ALDH1A1 (0.53) | SLC1A3SLC1A2SLC1A1KMT2ACYP1A2 | |
| SCHEMBL21843008 | 0.86 | ALDH1A1 (0.53) | SLC1A3SLC1A2SLC1A1KMT2ACYP1A2 | |
| SCHEMBL1195694 | 0.84 | SLC1A3 (0.53) | SLC1A3SLC1A2SLC1A1KMT2ACYP1A2 | |
| SCHEMBL4853198 | 0.84 | SLC1A3 (0.53) | SLC1A3SLC1A2SLC1A1KMT2ACYP1A2 | |
| SCHEMBL4908888 | 0.84 | SLC1A3 (0.53) | SLC1A3SLC1A2SLC1A1KMT2ACYP1A2 | |
| SCHEMBL25552099 | 0.84 | SLC1A3 (0.53) | SLC1A3SLC1A2SLC1A1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006024823-A9 | PYRIMIDINE SULPHONAMIDE DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS | ASTRAZENECA AB (SE) | 2007-03-15 | — | — | WO | disclosed |