Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 2/20 | 0.51 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.51 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 2/20 | 0.48 |
| ▸ | MMP8 | P22894 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1487164 | 1.00 | SLC1A3 (0.51) | SLC1A3SLC1A2SLC1A1KMT2ACYP1A2 | |
| SCHEMBL1362199 | 1.00 | SLC1A3 (0.51) | SLC1A3SLC1A2SLC1A1KMT2ACYP1A2 | |
| SCHEMBL1362196 | 1.00 | SLC1A3 (0.51) | SLC1A3SLC1A2SLC1A1KMT2ACYP1A2 | |
| SCHEMBL5569976 | 1.00 | SLC1A3 (0.51) | SLC1A3SLC1A2SLC1A1KMT2ACYP1A2 | |
| SCHEMBL21843005 | 0.86 | ALDH1A1 (0.53) | SLC1A3SLC1A2SLC1A1KMT2ACYP1A2 | |
| SCHEMBL21843008 | 0.86 | ALDH1A1 (0.53) | SLC1A3SLC1A2SLC1A1KMT2ACYP1A2 | |
| SCHEMBL1195694 | 0.84 | SLC1A3 (0.53) | SLC1A3SLC1A2SLC1A1KMT2ACYP1A2 | |
| SCHEMBL4853198 | 0.84 | SLC1A3 (0.53) | SLC1A3SLC1A2SLC1A1KMT2ACYP1A2 | |
| SCHEMBL4908888 | 0.84 | SLC1A3 (0.53) | SLC1A3SLC1A2SLC1A1KMT2ACYP1A2 | |
| SCHEMBL25552099 | 0.84 | SLC1A3 (0.53) | SLC1A3SLC1A2SLC1A1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0577040-B1 | Process for the preparation of (3R,5S)-6-hydroxy-3,5-O-isopropylidene-3,5-dihydroxy-hexanoic acid, tert.-butyl ester | HOECHST AG (DE) | 1997-09-24 | — | — | EP | claimed |
| US-8067398-B2 | Biodegradable polymers having a pre-determined chirality | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2011-11-29 | — | — | US | disclosed |
| US-20090318339-A1 | Biodegradable polymers having a pre-determined chirality | Yissum Research Development Company of The Hebrew Univerisity of Jerusalem (IL) | 2009-12-24 | — | — | US | disclosed |
| EP-1902084-A2 | BIODEGRADABLE POLYMERS HAVING A PRE-DETERMINED CHIRALITY | Yissum Research Development Company, of The Hebrew University of Jerusalem (IL) | 2008-03-26 | — | — | EP | disclosed |
| WO-2006129320-A2 | BIODEGRADABLE POLYMERS HAVING A PRE-DETERMINED CHIRALITY | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2006-12-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318339-A1 | Biodegradable polymers having a pre-determined chirality | PAICS, CD14, PCNA | SLC1A3 3072/4885SLC1A2 3630/4885SLC1A1 2728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.