Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | LAP3 | P28838 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 2/20 | 0.46 |
| ▸ | MMP8 | P22894 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21843008 | 1.00 | ALDH1A1 (0.53) | ALDH1A1LTA4HLAP3KMT2AMAPK1 | |
| SCHEMBL8930328 | 0.90 | LMNA (0.52) | ALDH1A1KMT2AL3MBTL1RCE1MMP9 | |
| SCHEMBL8930325 | 0.90 | LMNA (0.52) | ALDH1A1KMT2AL3MBTL1RCE1MMP9 | |
| SCHEMBL1362196 | 0.86 | SLC1A3 (0.51) | ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2 | |
| SCHEMBL1362201 | 0.86 | SLC1A3 (0.51) | ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2 | |
| SCHEMBL5569976 | 0.86 | SLC1A3 (0.51) | ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2 | |
| SCHEMBL1362199 | 0.86 | SLC1A3 (0.51) | ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2 | |
| SCHEMBL1487164 | 0.86 | SLC1A3 (0.51) | ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2 | |
| SCHEMBL487210 | 0.86 | RCE1 (0.47) | ALDH1A1LTA4HKMT2ARCE1MMP9 | |
| SCHEMBL487212 | 0.86 | RCE1 (0.47) | ALDH1A1LTA4HKMT2ARCE1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10596272-B2 | Vaccines against Streptococcus pneumoniae serotype 5 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2020-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10596272-B2 | Vaccines against Streptococcus pneumoniae serotype 5 | FUT5, SPAG5, IL5 | ALDH1A1 3515/4885LTA4H 1327/4885LAP3 1502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.