Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 7/20 | 0.49 |
| ▸ | KARS1 | Q15046 | 11/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2864564 | 0.88 | SYK (0.51) | SYKKARS1KDRMAP3K12 | |
| SCHEMBL13136408 | 0.87 | SYK (0.49) | SYKKARS1KDR | |
| SCHEMBL5570186 | 0.86 | SYK (0.51) | SYKKARS1MAP3K12 | |
| SCHEMBL2860076 | 0.85 | KARS1 (0.50) | SYKKARS1KDR | |
| SCHEMBL2870170 | 0.85 | SYK (0.49) | SYKKARS1KDR | |
| SCHEMBL13136398 | 0.85 | KARS1 (0.48) | SYKKARS1KDR | |
| SCHEMBL2867634 | 0.84 | SYK (0.51) | SYKKARS1KDR | |
| SCHEMBL2870364 | 0.84 | SYK (0.49) | SYKKARS1KDRMAP3K12 | |
| SCHEMBL2869504 | 0.84 | SYK (0.49) | SYKKARS1KDR | |
| SCHEMBL2862879 | 0.84 | SYK (0.49) | SYKKARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1854793-A1 | NOVEL AMINOPYRIDINE COMPOUND WITH Syk INHIBITORY ACTIVITY | Japan Tobacco, Inc. (JP) | 2007-11-14 | — | — | EP | disclosed |