Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | REN | P00797 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | CCR3 | P51677 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1039921 | 0.87 | ALDH1A1 (0.40) | ALDH1A1TSHRMAPK1MEN1LMNA | |
| SCHEMBL556327 | 0.87 | ALDH1A1 (0.40) | ALDH1A1TSHRMAPK1MEN1LMNA | |
| SCHEMBL1040623 | 0.87 | ALDH1A1 (0.40) | ALDH1A1TSHRMAPK1MEN1LMNA | |
| SCHEMBL556576 | 0.78 | TACR1 (0.37) | TSHRRENKCNH2CYP3A4 | |
| SCHEMBL6043574 | 0.77 | ALDH1A1 (0.53) | ALDH1A1TSHRMAPK1MEN1LMNA | |
| SCHEMBL1039923 | 0.74 | NPY1R (0.36) | ALDH1A1TSHRMEN1MAPTKMT2A | |
| SCHEMBL1039922 | 0.74 | NPY1R (0.36) | ALDH1A1TSHRMEN1MAPTKMT2A | |
| SCHEMBL534021 | 0.74 | ALDH1A1 (0.41) | ALDH1A1TSHRMAPK1MEN1LMNA | |
| SCHEMBL556532 | 0.72 | REN (0.37) | ALDH1A1MAPK1MEN1LMNAMAPT | |
| SCHEMBL556577 | 0.71 | REN (0.37) | RENKCNH2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120035214-A1 | RENIN INHIBITORS | MERCK CANADA INC. (CA) | 2012-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035214-A1 | RENIN INHIBITORS | REN, ACE, AGTR1 | ALDH1A1 900/4885TSHR 3174/4885MAPK1 1866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.