Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27224676 | 0.91 | EPHX2 (0.44) | CYP3A4ALDH1A1CYP19A1ESR1ESR2 | |
| SCHEMBL23792317 | 0.90 | CYP3A4 (0.41) | CYP3A4ALDH1A1CYP19A1ESR1ESR2 | |
| SCHEMBL20126694 | 0.84 | ALDH1A1 (0.55) | CYP3A4ALDH1A1CYP19A1ESR1ESR2 | |
| SCHEMBL6640643 | 0.84 | CPB2 (0.46) | ALDH1A1CYP19A1KMT2AMAPT | |
| SCHEMBL19699287 | 0.82 | ALDH1A1 (0.47) | CYP3A4ALDH1A1CYP19A1ESR1ESR2 | |
| SCHEMBL5401318 | 0.82 | ALDH1A1 (0.47) | CYP3A4ALDH1A1CYP19A1ESR1ESR2 | |
| SCHEMBL2059222 | 0.82 | ALDH1A1 (0.47) | CYP3A4ALDH1A1CYP19A1ESR1ESR2 | |
| Hydrochloric Acid SCHEMBL2106188 | 0.81 | ALDH1A1 (0.49) | CYP3A4ALDH1A1CYP19A1ESR1ESR2 | |
| SCHEMBL15180402 | 0.81 | ATM (0.46) | CYP3A4ALDH1A1CYP19A1ESR1ESR2 | |
| Hydrochloric Acid SCHEMBL5494194 | 0.81 | ALDH1A1 (0.49) | CYP3A4ALDH1A1CYP19A1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1057815-B1 | CYCLIC AMIDE COMPOUNDS | KOWA CO (JP) | 2007-09-05 | — | — | EP | disclosed |
| EP-0757685-B1 | NOVEL ACYCLIC AND CYCLIC AMIDES AS NEUROTRANSMITTER RELEASE ENHANCERS | PFIZER (US) | 2004-07-21 | — | — | EP | disclosed |
| US-6645957-B2 | Useful in preventing and treating allergic immunological diseases; treating asthma, atopic dermatitis, allergic rhinitis, inflammatory large bowel disease, contact dermatitis | KOWA CO., LTD. (JP) | 2003-11-11 | — | — | US | disclosed |
| US-20030096828-A1 | Cyclic amide compound | KOWA CO., LTD. (JP) | 2003-05-22 | — | — | US | disclosed |
| US-6448242-B1 | COMPOUND HAVING A STRONG INHIBITORY EFFECT ON THE PRODUCTION OF AN IGE ANTIBODY; ANTIALLERGENS | KOWA CO., LTD. (JP) | 2002-09-10 | — | — | US | disclosed |
| EP-1057815-A1 | CYCLIC AMIDE COMPOUNDS | Kowa Co., Ltd. (JP) | 2000-12-06 | — | — | EP | disclosed |
| US-5854232-A | Acyclic anc cyclic amides as neurotransmitter release enhancers | PFIZER INC. (US) | 1998-12-29 | — | — | US | disclosed |
| EP-0757685-A1 | NOVEL ACYCLIC AND CYCLIC AMIDES AS NEUROTRANSMITTER RELEASE ENHANCERS | PFIZER INC. (US) | 1997-02-12 | — | — | EP | disclosed |
| WO-1995029909-A1 | NOVEL ACYCLIC AND CYCLIC AMIDES AS NEUROTRANSMITTER RELEASE ENHANCERS | PFIZER INC. (US) | 1995-11-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030096828-A1 | Cyclic amide compound | CMA1, HRH2, HRH4 | CYP3A4 1130/4885ALDH1A1 2028/4885CYP19A1 172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.