Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5571465 | 0.93 | EPHX2 (1.00) | EPHX2EPHX1 | |
| SCHEMBL5573514 | 0.91 | EPHX2 (1.00) | EPHX2EPHX1 | |
| SCHEMBL2719283 | 0.91 | EPHX2 (1.00) | EPHX2EPHX1 | |
| SCHEMBL2717121 | 0.89 | EPHX2 (1.00) | EPHX2EPHX1 | |
| SCHEMBL2733490 | 0.89 | EPHX2 (0.80) | EPHX2EPHX1 | |
| SCHEMBL3964466 | 0.88 | EPHX2 (0.83) | EPHX2EPHX1 | |
| SCHEMBL4997818 | 0.87 | EPHX2 (0.79) | EPHX2EPHX1 | |
| SCHEMBL2716707 | 0.87 | EPHX2 (1.00) | EPHX2EPHX1 | |
| SCHEMBL27786321 | 0.86 | EPHX2 (0.76) | EPHX2EPHX1 | |
| SCHEMBL3350671 | 0.86 | EPHX2 (1.00) | EPHX2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10758511-B2 | Stable analogs of CYP450 lipid metabolites and inhibitors of soluble epoxide hydrolase | MASSACHUSETTS EYE AND EAR INFIRMARY (US) | 2020-09-01 | — | — | US | disclosed |
| EP-2528604-B1 | ACYL PIPERIDINE INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE | UNIV CALIFORNIA (US) | 2017-11-22 | — | — | EP | disclosed |
| EP-2528604-B1 | ACYL PIPERIDINE INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE | UNIV CALIFORNIA (US) | 2017-11-22 | — | — | EP | disclosed |
| US-20160200683-A1 | ACYL PIPERIDINE INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE | UNIV CALIFORNIA (US) | 2016-07-14 | — | — | US | disclosed |
| US-20160200683-A1 | ACYL PIPERIDINE INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE | UNIV CALIFORNIA (US) | 2016-07-14 | — | — | US | disclosed |
| US-9296693-B2 | Acyl piperidine inhibitors of soluble epoxide hydrolase | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-03-29 | — | — | US | disclosed |
| US-9296693-B2 | Acyl piperidine inhibitors of soluble epoxide hydrolase | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-03-29 | — | — | US | disclosed |
| US-20130143925-A1 | ACYL PIPERIDINE INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-06-06 | — | — | US | disclosed |
| US-20130143925-A1 | ACYL PIPERIDINE INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-06-06 | — | — | US | disclosed |
| WO-2012054093-A2 | ACYL PIPERIDINE INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10758511-B2 | Stable analogs of CYP450 lipid metabolites and inhibitors of soluble epoxide hydrolase | EPHX1, EPHX2, LIPG | EPHX2 2/4885EPHX1 1/4885 |
| US-20130143925-A1 | ACYL PIPERIDINE INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE | EPHX1, FAAH, FAAH2 | EPHX2 4/4885EPHX1 1/4885 |
| US-20160200683-A1 | ACYL PIPERIDINE INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE | EPHX1, FAAH, FAAH2 | EPHX2 4/4885EPHX1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.