Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | HSD17B3 | P37058 | 9/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5571166 | 0.77 | SLC17A5 (0.66) | SLC17A5KDM4EALDH1A1GLAGAA | |
| SCHEMBL5051764 | 0.73 | MEN1 (0.38) | SLC17A5KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL14456728 | 0.70 | SLC17A5 (0.68) | SLC17A5KDM4EALDH1A1GLAGAA | |
| SCHEMBL219274 | 0.69 | KDM4E (0.67) | KDM4EALDH1A1GLAGAAMEN1 | |
| SCHEMBL5622589 | 0.67 | SLC17A5 (0.80) | SLC17A5KDM4EALDH1A1GLAGAA | |
| SCHEMBL14456737 | 0.67 | SLC17A5 (0.80) | SLC17A5KDM4EALDH1A1GLAGAA | |
| SCHEMBL7338794 | 0.67 | ITGA4 (0.39) | KMT2ANPC1 | |
| SCHEMBL25178742 | 0.65 | PPARG (0.39) | ALDH1A1KMT2AMAPTHPGDLMNA | |
| SCHEMBL30510321 | 0.65 | PPARG (0.39) | ALDH1A1KMT2AMAPTHPGDLMNA | |
| SCHEMBL5839363 | 0.64 | GPR3 (0.37) | ALDH1A1GAAKMT2APOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9045507-B2 | Coumarin-based amino acids for use in enzyme activity and substrate specificity assays | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2015-06-02 | — | — | US | disclosed |
| US-20070031892-A1 | Novel coumarin-based amino acids for use in enzyme activity and substrate specificity assays | USC | 2007-02-08 | — | — | US | disclosed |