SCHEMBL5571377

SCHEMBL5571377

Cc1cc(-c2c(C)ccc(C(C)C)c2-c2cc(C)c(N=CCc3ccccn3)c(C)c2)cc(C)c1N=CCc1ccccn1

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.35
ALDH1A1 P00352 1/20 0.34
BRD4 O60885 4/20 0.33
PIP4K2C Q8TBX8 1/20 0.33
KDM4E B2RXH2 2/20 0.32
MAPT P10636 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
SYK P43405 2/20 0.31
LMNA P02545 1/20 0.30
HTT P42858 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30
GRIN1 Q05586 1/20 0.30
KCNH2 Q12809 1/20 0.30
GRIN2B Q13224 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5568545 0.93 ACHE (0.35) ACHEALDH1A1BRD4PIP4K2CKDM4E
SCHEMBL5571603 0.84 CYP1A2 (0.40) BRD4KDM4EMAPTSYKLMNA
SCHEMBL5571424 0.84 ESR1 (0.35) ALDH1A1BRD4KDM4EMAPTSYK
SCHEMBL5571172 0.84 ACHE (0.39) ACHEALDH1A1BRD4PIP4K2CKDM4E
SCHEMBL5569887 0.84 MAPT (0.37) ACHEALDH1A1BRD4PIP4K2CKDM4E
SCHEMBL3693189 0.83 BRD4 (0.40) BRD4KDM4EMAPTCYP1A2CYP2C9
SCHEMBL5571432 0.82 MEN1 (0.36) ACHEALDH1A1KDM4EMAPTLMNA
SCHEMBL5573240 0.82 ALDH1A1 (0.37) ALDH1A1BRD4KDM4EMAPTLMNA
Hydrochloric Acid SCHEMBL3692252 0.81 BRD4 (0.39) ALDH1A1BRD4KDM4EMAPTLMNA
Hydrochloric Acid SCHEMBL3691385 0.81 BRD4 (0.39) ALDH1A1BRD4KDM4EMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1753773-A1 TRANSITION METAL COMPOUNDS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION ExxonMobil Chemical Patents Inc. (US) 2007-02-21 EP claimed
WO-2005118605-A1 TRANSITION METAL COMPOUNDS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEMICAL PATENTS, INC. (US) 2005-12-15 WO claimed
EP-1753773-A1 TRANSITION METAL COMPOUNDS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION ExxonMobil Chemical Patents Inc. (US) 2007-02-21 EP disclosed
WO-2005118605-A1 TRANSITION METAL COMPOUNDS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEMICAL PATENTS, INC. (US) 2005-12-15 WO disclosed