Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.30 |
| ▸ | PPM1B | O75688 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9491416 | 0.86 | PPM1B (0.33) | PPM1BPTPN1 | |
| SCHEMBL11283030 | 0.81 | LMNA (0.46) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL11016268 | 0.73 | CYP3A4 (0.41) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL466763 | 0.73 | LMNA (0.37) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL4389785 | 0.73 | LMNA (0.41) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL14796418 | 0.67 | SIGMAR1 (0.30) | — | |
| SCHEMBL4004031 | 0.67 | ALDH1A1 (0.40) | LMNACHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL11282546 | 0.66 | LMNA (0.47) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL21243359 | 0.65 | TP53 (0.60) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL14422655 | 0.65 | LMNA (0.53) | LMNACHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1864323-A1 | REFRACTORY SOLID, ADHESIVE COMPOSITION, AND DEVICE, AND ASSOCIATED METHOD | General Electric Company (US) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006107660-A1 | REFRACTORY SOLID, ADHESIVE COMPOSITION, AND DEVICE, AND ASSOCIATED METHOD | GENERAL ELECTRIC COMPANY (US) | 2006-10-12 | — | — | WO | disclosed |