Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | AKT1 | P31749 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | LGMN | Q99538 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18742498 | 0.95 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3AKT1MEN1 | |
| SCHEMBL18769622 | 0.84 | ALDH1A1 (0.52) | MEN1NPC1ALDH1A1MAPTHTT | |
| Hydrochloric Acid SCHEMBL18742541 | 0.82 | ALDH1A1 (0.55) | MEN1NPC1ALDH1A1MAPTHTT | |
| SCHEMBL5572597 | 0.76 | LMNA (0.55) | SLC6A2SLC6A4SLC6A3MEN1ALDH1A1 | |
| SCHEMBL9092806 | 0.75 | LMNA (0.60) | MEN1NPC1ALDH1A1CYP1A2MAPT | |
| SCHEMBL6245150 | 0.75 | LMNA (0.60) | MEN1NPC1ALDH1A1CYP1A2MAPT | |
| SCHEMBL9093746 | 0.74 | LMNA (0.71) | MEN1NPC1ALDH1A1CYP1A2MAPT | |
| SCHEMBL4699438 | 0.73 | AGXT (0.54) | SLC6A2SLC6A4SLC6A3AKT1MEN1 | |
| SCHEMBL2175616 | 0.72 | LMNA (0.62) | MEN1NPC1ALDH1A1CYP1A2MAPT | |
| SCHEMBL18769493 | 0.72 | HPGD (0.40) | AKT1NPC1ALDH1A1CYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745009-B1 | HETEROARYL SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2012-11-14 | — | — | EP | claimed |
| US-20070129369-A1 | Heteroaryl substituted cyclohexyl-1,4-diamine compounds | GRUENENTHAL GMBH (DE) | 2007-06-07 | — | — | US | claimed |
| US-20070129369-A1 | Heteroaryl substituted cyclohexyl-1,4-diamine compounds | GRUENENTHAL GMBH (DE) | 2007-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129369-A1 | Heteroaryl substituted cyclohexyl-1,4-diamine compounds | DDC, DPYD, PKD1 | SLC6A2 3205/4885SLC6A4 3073/4885SLC6A3 2365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.