SCHEMBL557278

SCHEMBL557278

O=C(O)C(O)(O)CCl.[AlH3].[NaH]

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.35
ALDH1A1 P00352 3/20 0.35
TP53 P04637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11489802 0.97
SCHEMBL6257440 0.94
SCHEMBL11050416 0.67
SCHEMBL812277 0.65
SCHEMBL21893406 0.65 ALDH1A1 (0.39) TSHRALDH1A1TP53
SCHEMBL9139060 0.65 TSHR (0.41) TSHRALDH1A1TP53
SCHEMBL5354734 0.65
SCHEMBL7969652 0.65 ALDH1A1 (0.52) TSHRALDH1A1
SCHEMBL5697455 0.65
SCHEMBL9321573 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 297 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10869817-B2 Antiperspirant stick compositions Henkel IP & Holding GmbH 2020-12-22 US claimed
US-10835483-B2 Antiperspirant stick compositions Henkel IP & Holding GmbH 2020-11-17 US claimed
US-10821068-B2 Antiperspirant stick compositions Henkel IP & Holding GmbH (DE) 2020-11-03 US claimed
EP-3694473-A1 ANTIPERSPIRANT STICK COMPOSITIONS Henkel IP & Holding GmbH (DE) 2020-08-19 EP claimed
WO-2019074643-A1 ANTIPERSPIRANT STICK COMPOSITIONS Henkel IP & Holding GmbH (DE) 2019-04-18 WO claimed
WO-2019074647-A1 ANTIPERSPIRANT STICK COMPOSITIONS Henkel IP & Holding GmbH (DE) 2019-04-18 WO claimed
US-20190105239-A1 ANTIPERSPIRANT STICK COMPOSITIONS Henkel IP & Holding GmbH (DE) 2019-04-11 US claimed
US-20190105257-A1 ANTIPERSPIRANT STICK COMPOSITIONS Henkel IP & Holding GmbH (DE) 2019-04-11 US claimed
US-20190105255-A1 ANTIPERSPIRANT STICK COMPOSITIONS Henkel IP & Holding GmbH (DE) 2019-04-11 US claimed
US-20190105256-A1 ANTIPERSPIRANT STICK COMPOSITIONS Henkel IP & Holding GmbH (DE) 2019-04-11 US claimed
US-20160206534-A1 ANTIPERSPIRANT COSMETIC AGENTS HAVING POLYCARBOXYLIC ACIDS HENKEL AG & CO. KGAA (DE) 2016-07-21 US claimed
US-20160199287-A1 COSMETIC ANTIPERSPIRANTS WITH ALKYLSUPHONIC ACIDS HENKEL AG & CO. KGAA (DE) 2016-07-14 US claimed
EP-0972512-B1 Cosmetic composition containing pigments, an antiperspirant and a solid elastomeric partially crosslinked organopolysiloxane, use of such a composition OREAL (FR) 2002-01-02 EP claimed
US-6251412-B1 USE IN MAKE-UP, TO IMPROVE THE STAYING POWER OF THE COLOR OF THE COMPOSITION L'OREAL (FR) 2001-06-26 US claimed
EP-0318206-A1 Deodorant gel stick THE PROCTER & GAMBLE COMPANY (US) 1989-05-31 EP claimed
US-4816261-A Deodorant gel stick THE PROCTER & GAMBLE COMPANY (US) 1989-03-28 US claimed
US-4781917-A FREE OF UNBOUND WATER THE PROCTOR & GAMBLE COMPANY (US) 1988-11-01 US claimed
US-12605321-B2 Personal care compositions COLGATE-PALMOLIVE COMPANY (US) 2026-04-21 US disclosed
WO-1990010635-A1 NOVEL ANTIPERSPIRANT ADDUCT COMPOSITIONS AND PROCESS FOR MAKING SAME THE GILLETTE COMPANY (US) 1990-09-20 WO disclosed
US-4781917-A FREE OF UNBOUND WATER THE PROCTOR & GAMBLE COMPANY (US) 1988-11-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160199287-A1 COSMETIC ANTIPERSPIRANTS WITH ALKYLSUPHONIC ACIDS HRH3, HRH2, HRH1 TSHR 2406/4885ALDH1A1 1171/4885TP53 2676/4885
US-20160206534-A1 ANTIPERSPIRANT COSMETIC AGENTS HAVING POLYCARBOXYLIC ACIDS H1-0, H1-10, H1-5 TSHR 3027/4885ALDH1A1 220/4885TP53 728/4885
US-12605321-B2 Personal care compositions SMURF1, S100A10, SMURF2 TSHR 3822/4885ALDH1A1 3142/4885TP53 1098/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.