Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 4/20 | 0.31 |
| ▸ | NPC1 | O15118 | 3/20 | 0.31 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18092970 | 0.83 | KMT2A (0.32) | LMNANPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL11519504 | 0.81 | HSD17B3 (0.34) | PTGS2PTGS1LMNANPC1RAB9A | |
| SCHEMBL1480337 | 0.76 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL11372909 | 0.73 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL5573370 | 0.71 | PTGS2 (0.32) | PTGS2PTGS1ALOX5 | |
| SCHEMBL442745 | 0.71 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL6641316 | 0.71 | OAT (0.37) | LMNATSHRALDH1A1 | |
| SCHEMBL5573120 | 0.70 | PTGS2 (0.32) | PTGS2PTGS1ALOX5BCHEACHE | |
| SCHEMBL11373278 | 0.69 | PTPN1 (0.30) | — | |
| SCHEMBL14879756 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1790630-B1 | Derivatives of 3-cyclopropyl-1-propanone compounds and their use in perfume compositions | INT FLAVORS & FRAGRANCES INC (US) | 2014-01-08 | — | — | EP | claimed |
| EP-1790630-B1 | Derivatives of 3-cyclopropyl-1-propanone compounds and their use in perfume compositions | INT FLAVORS & FRAGRANCES INC (US) | 2014-01-08 | — | — | EP | disclosed |
| EP-1790630-B1 | Derivatives of 3-cyclopropyl-1-propanone compounds and their use in perfume compositions | INT FLAVORS & FRAGRANCES INC (US) | 2014-01-08 | — | — | EP | disclosed |
| EP-1790630-A1 | Derivatives of 3-cyclopropyl-1-propanone compounds and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES, INC. (US) | 2007-05-30 | — | — | EP | disclosed |
| EP-1790630-A1 | Derivatives of 3-cyclopropyl-1-propanone compounds and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES, INC. (US) | 2007-05-30 | — | — | EP | disclosed |
| US-7074967-B1 | Derivatives of 3-cyclopropyl-1-propanone compounds and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2006-07-11 | — | — | US | disclosed |