Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 4/20 | 0.63 |
| ▸ | CTSL | P07711 | 3/20 | 0.53 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.53 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.53 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.53 |
| ▸ | CMA1 | P23946 | 1/20 | 0.52 |
| ▸ | CTRC | Q99895 | 1/20 | 0.52 |
| ▸ | MME | P08473 | 2/20 | 0.52 |
| ▸ | ANPEP | P15144 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20204723 | 1.00 | CTSB (0.63) | CTSBCTSLPSMB5PSMB2PSMB1 | |
| SCHEMBL20204725 | 1.00 | CTSB (0.63) | CTSBCTSLPSMB5PSMB2PSMB1 | |
| SCHEMBL7144589 | 0.90 | CTSB (0.61) | CTSBCTSLPSMB5PSMB2PSMB1 | |
| SCHEMBL13706577 | 0.90 | CTSB (0.61) | CTSBCTSLPSMB5PSMB2PSMB1 | |
| SCHEMBL8259852 | 0.88 | CTSB (0.62) | CTSBCTSLPSMB5PSMB2PSMB1 | |
| SCHEMBL13933704 | 0.88 | CTSB (0.62) | CTSBCTSLPSMB5PSMB2PSMB1 | |
| SCHEMBL24178168 | 0.88 | CTSB (0.58) | CTSBCTSLPSMB5PSMB2CMA1 | |
| SCHEMBL30371890 | 0.88 | CTSB (0.58) | CTSBCTSLPSMB5PSMB2PSMB1 | |
| SCHEMBL24178174 | 0.88 | CTSB (0.58) | CTSBCTSLPSMB5PSMB2CMA1 | |
| SCHEMBL20204721 | 0.88 | CTSB (0.55) | CTSBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070265208-A1 | Association of calpain inhibitors and reactive oxygen species trapping agents | SOCIETE DE CONSEILS DE RECHERCHE ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) | 2007-11-15 | — | — | US | claimed |
| US-7244711-B2 | Association of calpain inhibitors and reactive oxygen species trapping agents | SOCIETE DE CONSEILS DE RECHERCHES ET D' 'APPLICATIONS SCIENTIFIQUES S.C.R.A.S (FR) | 2007-07-17 | — | — | US | claimed |
| EP-1337269-B1 | ASSOCIATION OF CALPAIN INHIBITORS AND REACTIVE OXYGEN SPECIES TRAPPING AGENTS | SOD CONSEILS RECH APPLIC (FR) | 2006-11-08 | — | — | EP | claimed |
| US-20040053851-A1 | Association of calpain inhibitors and reactive oxygen species trapping agents | IPSEN PHARMA S.A.S. (FR) | 2004-03-18 | — | — | US | claimed |
| US-20070265208-A1 | Association of calpain inhibitors and reactive oxygen species trapping agents | SOCIETE DE CONSEILS DE RECHERCHE ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) | 2007-11-15 | — | — | US | disclosed |
| US-7244711-B2 | Association of calpain inhibitors and reactive oxygen species trapping agents | SOCIETE DE CONSEILS DE RECHERCHES ET D' 'APPLICATIONS SCIENTIFIQUES S.C.R.A.S (FR) | 2007-07-17 | — | — | US | disclosed |
| EP-1337269-B1 | ASSOCIATION OF CALPAIN INHIBITORS AND REACTIVE OXYGEN SPECIES TRAPPING AGENTS | SOD CONSEILS RECH APPLIC (FR) | 2006-11-08 | — | — | EP | disclosed |
| US-20040053851-A1 | Association of calpain inhibitors and reactive oxygen species trapping agents | IPSEN PHARMA S.A.S. (FR) | 2004-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265208-A1 | Association of calpain inhibitors and reactive oxygen species trapping agents | CAPNS1, CAPN1, CAPN2 | CTSB 64/4885CTSL 126/4885PSMB5 313/4885 |
| US-20040053851-A1 | Association of calpain inhibitors and reactive oxygen species trapping agents | CAPN2, CAPN1, CAPN9 | CTSB 32/4885CTSL 98/4885PSMB5 298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.