SCHEMBL5572957

SCHEMBL5572957

CCCCCCCCCCCCCCCCCCCCCCCCCCCCC(O)[Si](OCC)(OCC)OCC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.41
SPHK1 Q9NYA1 2/20 0.41
FFAR1 O14842 2/20 0.41
LMNA P02545 2/20 0.40
CYP2D6 P10635 2/20 0.38
GMNN O75496 1/20 0.38
POLB P06746 1/20 0.38
THPO P40225 1/20 0.38
MTOR P42345 1/20 0.38
BLM P54132 1/20 0.38
KDM4E B2RXH2 1/20 0.38
TP53 P04637 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
MAPT P10636 1/20 0.38
CETP P11597 1/20 0.38
HTT P42858 1/20 0.38
UBE2N P61088 1/20 0.38
OPRM1 P35372 1/20 0.38
SMPD1 P17405 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22370107 1.00 GPR84 (0.41) GPR84SPHK1FFAR1LMNACYP2D6
SCHEMBL1144280 1.00 GPR84 (0.41) GPR84SPHK1FFAR1LMNACYP2D6
SCHEMBL22370105 1.00 GPR84 (0.41) GPR84SPHK1FFAR1LMNACYP2D6
SCHEMBL28690771 0.98 OPRM1 (0.39) GPR84SPHK1FFAR1LMNACYP2D6
SCHEMBL28690703 0.82 LMNA (0.30) LMNA
SCHEMBL18185950 0.81 ACACB (0.30)
SCHEMBL22370102 0.81 GPR84 (0.42) GPR84SPHK1FFAR1LMNACYP2D6
SCHEMBL4436083 0.81 GPR84 (0.42) GPR84SPHK1FFAR1LMNACYP2D6
SCHEMBL5575271 0.81 GPR84 (0.42) GPR84SPHK1FFAR1LMNACYP2D6
SCHEMBL27610755 0.81 GPR84 (0.42) GPR84SPHK1FFAR1LMNACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007019478-A2 DRUG DELIVERY FROM IMPLANTS USING SELF-ASSEMBLED MONOLAYERS - THERAPEUTIC SAMS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2007-02-15 WO disclosed