SCHEMBL5573444

SCHEMBL5573444

C=C(C)c1cc(C(C)C)cc(C(C)C)c1

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.37
GABRB2 P47870 1/20 0.37
FABP3 P05413 2/20 0.35
FABP4 P15090 2/20 0.35
FABP5 Q01469 1/20 0.34
CNR1 P21554 1/20 0.33
HTT P42858 2/20 0.32
TRPA1 O75762 1/20 0.32
PTGS1 P23219 1/20 0.32
CACNA1C Q13936 1/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31
ALOX12 P18054 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1408591 0.95 GABRA1 (0.37) GABRA1GABRB2FABP3FABP4FABP5
SCHEMBL5571987 0.82 GABRA1 (0.38) GABRA1GABRB2FABP3FABP4FABP5
SCHEMBL16960765 0.79 GABRA1 (0.39) GABRA1GABRB2FABP3FABP4FABP5
SCHEMBL31529664 0.78 MAPT (0.46) HTTTRPA1PTGS1CACNA1CKDM4E
SCHEMBL299924 0.78 MAPT (0.46) HTTTRPA1PTGS1CACNA1CKDM4E
SCHEMBL26169259 0.76 MEN1 (0.33) GAA
SCHEMBL717192 0.75 HTT (0.52) CNR1HTTTRPA1PTGS1CACNA1C
SCHEMBL8146335 0.75 CA5A (0.48) GABRA1GABRB2FABP3FABP4FABP5
SCHEMBL16956111 0.75 GABRA1 (0.33) GABRA1GABRB2FABP3FABP4FABP5
Hydrogen Peroxide SCHEMBL3271571 0.74 FABP3 (0.52) GABRA1GABRB2FABP3FABP4FABP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1803700-A2 Method for the dehydrogenation of diisopropyl benezene Mitsui Chemicals, Inc. (JP) 2007-07-04 EP disclosed
US-20070065763-A1 Photothermographic material FUJI PHOTO FILM CO., LTD. 2007-03-22 US disclosed
CN-1243702-C Method of dehydrogenating triisopropylbenzene and diisopropylbenzene MITSUI CHEMICALS INC (JP) 2006-03-01 CN disclosed
US-6743959-B1 CHROMIUM FREE CATALYTIC SYNTHESIS OF UNSATURATED CHEMICAL INTERMEDIATES MITSUI CHEMICALS, INC. (JP) 2004-06-01 US disclosed
CN-1382112-A Process for the dehydrogenation of triisopropylbenzene and diisopropylbenzene MITSUI CHEMICALS INC (JP) 2002-11-27 CN disclosed
EP-1219582-A1 METHOD OF DEHYDROGENATING TRIISOPROPYLBENZENE AND DIISOPROPYLBENZENE Mitsui Chemicals, Inc. (JP) 2002-07-03 EP disclosed