SCHEMBL717192

SCHEMBL717192

C=C(C)c1ccc(C(C)C)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.52
CYP2C9 P11712 3/20 0.45
USP5 P45974 1/20 0.44
TYR P14679 2/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
RAB9A P51151 2/20 0.38
CYP2D6 P10635 1/20 0.38
HIF1A Q16665 1/20 0.38
NPC1 O15118 1/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38
POLB P06746 1/20 0.37
RXRA P19793 1/20 0.37
RXRB P28702 1/20 0.37
TRPA1 O75762 1/20 0.37
PTGS1 P23219 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21093726 0.93 HTT (0.47) HTTCYP2C9USP5TYRMEN1
SCHEMBL11511447 0.91 ESR1 (0.48) HTTCYP2C9USP5TYRLMNA
SCHEMBL10603240 0.85 ESR1 (0.50) HTTCYP2C9USP5MEN1KMT2A
Isopropylbenzene SCHEMBL4798187 0.84 LMNA (0.44) CYP2C9MEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL12643093 0.83 ACACB (0.46) HTTRAB9AMAPTRXRARXRB
SCHEMBL12227194 0.83 RXRA (0.49) HTTMEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL7550553 0.83 NOS3 (0.45) HTTCYP2C9USP5MEN1KMT2A
SCHEMBL8441986 0.83 HTT (0.35) HTTCYP2C9USP5
SCHEMBL20433702 0.81 ADRB2 (0.48) HTTKMT2ALMNAHIF1AMAPT
SCHEMBL56361 0.81 MAPT (0.40) HTTMEN1KMT2ASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 297 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118271496-A Isoalkenyl terpolymer containing oxygen polar groups and preparation method thereof 常州汉韦聚合物有限公司 2024-07-02 CN claimed
JP-4372014-B2 2009-11-25 JP claimed
EP-1803700-A2 Method for the dehydrogenation of diisopropyl benezene Mitsui Chemicals, Inc. (JP) 2007-07-04 EP claimed
JP-2006506415-A 2006-02-23 JP claimed
EP-1599487-A1 PHOSPHINIC ACID ANALOGS OF GLUTAMATE Givaudan SA (CH) 2005-11-30 EP claimed
WO-2004048394-A1 PHOSPHINIC ACID ANALOGS OF GLUTAMATE GIVAUDAN SA (CH) 2004-06-10 WO claimed
US-6743959-B1 CHROMIUM FREE CATALYTIC SYNTHESIS OF UNSATURATED CHEMICAL INTERMEDIATES MITSUI CHEMICALS, INC. (JP) 2004-06-01 US claimed
WO-2004043971-A1 PHOSPHINIC ACID ANALOGS OF GLUTAMATE GIVAUDAN SA (CH) 2004-05-27 WO claimed
EP-1219582-A1 METHOD OF DEHYDROGENATING TRIISOPROPYLBENZENE AND DIISOPROPYLBENZENE Mitsui Chemicals, Inc. (JP) 2002-07-03 EP claimed
EP-0624576-B1 Monomeric aminoplasts crosslinking agents CYTEC TECH CORP (US) 2000-10-25 EP claimed
US-5453344-A Styrene block copolymer XEROX CORPORATION (US) 1995-09-26 US claimed
EP-0340976-B1 Acrylic polymers PPG INDUSTRIES INC (US) 1995-06-28 EP claimed
EP-0641756-A1 Method of preparing unsaturated dimers of alpha-methylstyrenes GOI CHEMICAL COMPANY, LTD. (JP) 1995-03-08 EP claimed
EP-0437268-B1 Method for binding a non-woven fiber-web by using a formaldehyde-free binder composition and products manufactured therewith NAT STARCH CHEM INVEST (US) 1994-01-12 EP claimed
EP-0351534-B1 POLYFUNCTIONAL MONOMERS AND PROCESS FOR PRODUCTION THEREOF MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-05-12 EP claimed
EP-0270318-B1 MODIFIED STRUCTURAL ADHESIVES LORD CORPORATION (US) 1992-04-15 EP claimed
US-4956225-A Transparency with a polymeric substrate and toner receptive coating XEROX CORPORATION (US) 1990-09-11 US claimed
US-4340690-A Cyclic organo carbonate and sulfite coupling agents for living polymers of conjugated dienes THE GOODYEAR TIRE & RUBBER COMPANY (US) 1982-07-20 US claimed
US-4340691-A Linear organo carbonate coupling agents for living polymers of conjugated dienes THE GOODYEAR TIRE & RUBBER COMPANY (US) 1982-07-20 US claimed
US-4198535-A HEATING WITH SILICA-ALUMINA CATALYST MITSUI PETROCHEMICAL INDUSTRIES LTD. (JP) 1980-04-15 US claimed