Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 8/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RHEB | Q15382 | 2/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4598186 | 0.86 | ALDH1A1 (0.58) | ALDH1A1HPGDBRAFCA12CA1 | |
| SCHEMBL14571144 | 0.82 | NPC1 (0.41) | ALDH1A1HPGDBRAFKMT2A | |
| SCHEMBL4597308 | 0.80 | ALDH1A1 (0.53) | ALDH1A1HPGDBRAFKDRKMT2A | |
| SCHEMBL1185621 | 0.78 | ALDH1A1 (0.63) | ALDH1A1ADRB2ADRB1ADRB3CA12 | |
| SCHEMBL4597726 | 0.76 | KDM4E (0.60) | ALDH1A1ADRB2ADRB1ADRB3HRH3 | |
| SCHEMBL2264443 | 0.75 | KDM4E (0.50) | ALDH1A1HPGDCHEK2 | |
| SCHEMBL10165326 | 0.74 | GABRG2 (0.44) | ALDH1A1HPGDS | |
| SCHEMBL3926634 | 0.73 | HSD17B10 (0.50) | ALDH1A1HPGDBRAFKDRCHEK2 | |
| SCHEMBL5572729 | 0.73 | ALDH1A1 (0.37) | ALDH1A1HPGDBRAFKDRHRH3 | |
| SCHEMBL580094 | 0.73 | PARP10 (0.46) | ALDH1A1HPGDBRAFKDRHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070066624-A1 | Chemokine receptor binding compounds | ANORMED, INC. (CA) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066624-A1 | Chemokine receptor binding compounds | CCR5, CCR4, CCR1 | ALDH1A1 3484/4885HPGD 1736/4885BRAF 3162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.