SCHEMBL5574192

SCHEMBL5574192

N[C@H](Cc1ccc(Oc2ccc(O)cc2I)c(I)c1I)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.52
MEN1 O00255 6/20 0.52
BLM P54132 3/20 0.52
PPARG P37231 3/20 0.52
NR1I2 O75469 2/20 0.52
AGTR2 P50052 1/20 0.52
PCNA P12004 2/20 0.48
LMNA P02545 6/20 0.47
HSD17B10 Q99714 4/20 0.47
NPSR1 Q6W5P4 3/20 0.47
ALDH1A1 P00352 3/20 0.47
CYP3A4 P08684 3/20 0.47
MAPT P10636 3/20 0.47
ALOX15 P16050 3/20 0.47
ADORA3 P0DMS8 3/20 0.47
KDM4E B2RXH2 2/20 0.47
NFKB1 P19838 2/20 0.47
PMP22 Q01453 2/20 0.47
TSHR P16473 2/20 0.47
HTR1A P08908 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL282065 1.00 KMT2A (0.52) KMT2AMEN1BLMPPARGNR1I2
SCHEMBL230513 1.00 KMT2A (0.52) KMT2AMEN1BLMPPARGNR1I2
SCHEMBL6350388 0.99 KMT2A (0.51) KMT2AMEN1BLMPPARGNR1I2
SCHEMBL16390915 0.88 KMT2A (0.47) KMT2AMEN1BLMPPARGNR1I2
SCHEMBL10495232 0.87 BLM (0.41) KMT2AMEN1BLMPPARGNR1I2
SCHEMBL10537170 0.87 BLM (0.41) KMT2AMEN1BLMPPARGNR1I2
Hydrochloric Acid SCHEMBL10529768 0.86 BLM (0.41) KMT2AMEN1BLMPPARGNR1I2
SCHEMBL836727 0.85 KMT2A (0.61) KMT2AMEN1BLMPPARGNR1I2
SCHEMBL4355962 0.85 KMT2A (0.61) KMT2AMEN1BLMPPARGNR1I2
SCHEMBL10938099 0.85 KMT2A (0.61) KMT2AMEN1BLMPPARGNR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7182912-B2 Fluid handling apparatus for an automated analyzer BAYER CORPORATION (US) 2007-02-27 US disclosed
US-20060013729-A1 Fluid handling apparatus for an automated analyzer SIEMENS HEALTHCARE DIAGNOSTICS INC. 2006-01-19 US disclosed
US-20050266570-A1 Cuvette for an automated analyzer BAYER CORPORATION 2005-12-01 US disclosed
EP-0984283-B1 Isolation means and method of evacuating liquid from a cuvette BAYER AG (US) 2003-10-29 EP disclosed
EP-0984270-B1 Luminometer BAYER AG (US) 2003-09-24 EP disclosed
EP-0819941-B1 Reagent container and cover BAYER AG (US) 2003-08-20 EP disclosed
EP-1308731-A2 Apparatus for use in automated analyzer Bayer Corporation (US) 2003-05-07 EP disclosed
US-6555062-B1 Specifically suited for performing heterogeneous binding assay protocols, particularly immunoassays. BAYER CORPORATION 2003-04-29 US disclosed
US-6498037-B1 PROVIDING A FIRST SET OF CONTAINERS CONTAINING REAGENTS IN CONSECUTIVE LOCATIONS ALONG A FIRST CIRCULAR PATH HAVING AN AXIS OF ROTATION, EACH OF THE CONTAINERS HAVING BAR CODE, WHICH IDENTIFIES THE REAGENT IT CONTAINS, ABOUT AT LEAST A BAYER CORPORATION 2002-12-24 US disclosed
US-6436349-B1 HETEROGENEOUS IMMUNOASSAYS IN WHICH PARAMAGNETIC PARTICLES ARE SOLID PHASE REAGENT AND LABELED REAGENT (TRACER REAGENT) INCLUDES A CHEMILUMINESCENT LABEL; REAGENT TRANSPORT APPARATUS BAYER CORPORATION 2002-08-20 US disclosed
EP-0502638-B1 Feed and orientation mechanism for cuvettes BAYER AG (US) 2000-05-31 EP disclosed
EP-0984270-A2 Luminometer Ciba Corning Diagnostics Corp. (US) 2000-03-08 EP disclosed
EP-0984283-A2 Isolation means and method of evacuating liquid from a cuvette Ciba Corning Diagnostics Corp. (US) 2000-03-08 EP disclosed
EP-0984284-A2 Apparatus for use in automated analyzer Ciba Corning Diagnostics Corp. (US) 2000-03-08 EP disclosed
EP-0819941-A2 Reagent container and cover Ciba Corning Diagnostics Corp. (US) 1998-01-21 EP disclosed
EP-0123528-A1 Pharmaceutical composition for the treatment of hair loss Mortimer, Christopher Harry, Dr. (GB) 1984-10-31 EP disclosed
US-3917832-A Compositions comprising d-thyroxine and d-triiodothyronine MERCK PATENT GMBH 1975-11-04 US disclosed
US-3917832-A Compositions comprising d-thyroxine and d-triiodothyronine MERCK PATENT GMBH 1975-11-04 US disclosed