Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | BLM | P54132 | 3/20 | 0.51 |
| ▸ | PPARG | P37231 | 3/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.51 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.51 |
| ▸ | PCNA | P12004 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 6/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5574192 | 0.99 | KMT2A (0.52) | KMT2AMEN1BLMPPARGNR1I2 | |
| SCHEMBL282065 | 0.99 | KMT2A (0.52) | KMT2AMEN1BLMPPARGNR1I2 | |
| SCHEMBL230513 | 0.99 | KMT2A (0.52) | KMT2AMEN1BLMPPARGNR1I2 | |
| SCHEMBL16390915 | 0.87 | KMT2A (0.47) | KMT2AMEN1BLMPPARGNR1I2 | |
| SCHEMBL10537170 | 0.86 | BLM (0.41) | KMT2AMEN1BLMPPARGNR1I2 | |
| SCHEMBL10495232 | 0.86 | BLM (0.41) | KMT2AMEN1BLMPPARGNR1I2 | |
| Hydrochloric Acid SCHEMBL10529768 | 0.85 | BLM (0.41) | KMT2AMEN1BLMPPARGNR1I2 | |
| SCHEMBL4355962 | 0.84 | KMT2A (0.61) | KMT2AMEN1BLMPPARGNR1I2 | |
| SCHEMBL10938099 | 0.84 | KMT2A (0.61) | KMT2AMEN1BLMPPARGNR1I2 | |
| SCHEMBL5583934 | 0.84 | NR1I2 (0.36) | KMT2AMEN1BLMPPARGNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117821369-A | Use of small molecules to enhance MAFA expression in pancreatic endocrine cells | 詹森生物科技公司 | 2024-04-05 | — | — | CN | disclosed |
| US-20050221464-A1 | Method for culturing hcv virus in vitro | BIOMERIEUX (FR) | 2005-10-06 | — | — | US | disclosed |