SCHEMBL10495232

SCHEMBL10495232

COC(=O)C(N)Cc1ccc(Oc2ccc(O)cc2I)c(I)c1I

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BLM P54132 2/20 0.41
KMT2A Q03164 2/20 0.41
NR1I2 O75469 1/20 0.41
PPARG P37231 1/20 0.41
AGTR2 P50052 1/20 0.41
MEN1 O00255 1/20 0.41
OPRK1 P41145 7/20 0.39
ALDH1A1 P00352 2/20 0.38
PCNA P12004 2/20 0.36
KDM4E B2RXH2 1/20 0.34
LMNA P02545 1/20 0.34
CYP3A4 P08684 1/20 0.34
HTR1A P08908 1/20 0.34
ADORA3 P0DMS8 1/20 0.34
MAPT P10636 1/20 0.34
ALOX15 P16050 1/20 0.34
TSHR P16473 1/20 0.34
NFKB1 P19838 1/20 0.34
HTR2A P28223 1/20 0.34
HTR2C P28335 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10537170 1.00 BLM (0.41) BLMKMT2ANR1I2PPARGAGTR2
Hydrochloric Acid SCHEMBL10529768 0.99 BLM (0.41) BLMKMT2ANR1I2PPARGAGTR2
SCHEMBL230513 0.87 KMT2A (0.52) BLMKMT2ANR1I2PPARGAGTR2
SCHEMBL5574192 0.87 KMT2A (0.52) BLMKMT2ANR1I2PPARGAGTR2
SCHEMBL282065 0.87 KMT2A (0.52) BLMKMT2ANR1I2PPARGAGTR2
SCHEMBL6350388 0.86 KMT2A (0.51) BLMKMT2ANR1I2PPARGAGTR2
Hydrochloric Acid SCHEMBL10531318 0.85 MEN1 (0.48) BLMKMT2ANR1I2PPARGAGTR2
SCHEMBL5583934 0.80 NR1I2 (0.36) BLMKMT2ANR1I2PPARGAGTR2
SCHEMBL16390915 0.78 KMT2A (0.47) BLMKMT2ANR1I2PPARGAGTR2
Terbutaline SCHEMBL9718449 0.76 KMT2A (0.45) BLMKMT2ANR1I2PPARGAGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109212194-B Kit for quantitatively detecting transtriiodothyronine 郑州安图生物工程股份有限公司 2020-06-16 CN claimed
US-20260115330-A1 RADIOPAQUE MULTI-ARM POLYMERS FOR MEDICAL APPLICATIONS BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-04-30 US disclosed
US-20250059237-A1 METHODS OF FORMING RADIOPAQUE PEPTIDES AND MEDICAL HYDROGELS FORMED THEREFROM BOSTON SCIENTIFIC SCIMED, INC. (US) 2025-02-20 US disclosed
US-20240335568-A1 RADIOPAQUE POLYSACCHARIDE HYDROGELS AND METHODS OF MAKING THE SAME BOSTON SCIENTIFIC SCIMED, INC. (US) 2024-10-10 US disclosed
CN-109212194-B Kit for quantitatively detecting transtriiodothyronine 郑州安图生物工程股份有限公司 2020-06-16 CN disclosed
US-4879249-A IMMUNOASSAY BALDWIN THOMAS O (US) 1989-11-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240335568-A1 RADIOPAQUE POLYSACCHARIDE HYDROGELS AND METHODS OF MAKING THE SAME CD44, ALG1, CA13 BLM 169/4885KMT2A 3066/4885NR1I2 4554/4885
US-20250059237-A1 METHODS OF FORMING RADIOPAQUE PEPTIDES AND MEDICAL HYDROGELS FORMED THEREFROM HDGF, IAPP, QRFPR BLM 615/4885KMT2A 3609/4885NR1I2 3622/4885
US-20260115330-A1 RADIOPAQUE MULTI-ARM POLYMERS FOR MEDICAL APPLICATIONS KLK3, BRDT, BPHL BLM 1467/4885KMT2A 2276/4885NR1I2 3107/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.