Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 12/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5268590 | 0.83 | ALDH1A1 (0.55) | GAAALOX5MAPTALDH1A1HPGD | |
| SCHEMBL5573968 | 0.83 | HPGD (0.43) | ALOX5MAPTALDH1A1HPGDKDM4E | |
| SCHEMBL5266671 | 0.78 | POLB (0.41) | GAAALOX5MAPTALDH1A1HPGD | |
| SCHEMBL5268810 | 0.77 | MAPT (0.52) | GAAALOX5MAPTALDH1A1HPGD | |
| SCHEMBL5573956 | 0.76 | PKM (0.44) | GAAALOX5MAPTALDH1A1HPGD | |
| SCHEMBL5270537 | 0.72 | ALDH1A1 (0.54) | GAAMAPTALDH1A1HPGDKDM4E | |
| SCHEMBL5516043 | 0.71 | POLB (0.43) | GAAMAPTALDH1A1HPGDKDM4E | |
| SCHEMBL27549077 | 0.71 | NR1I2 (0.60) | GAAALOX5MAPTALDH1A1HPGD | |
| SCHEMBL1193860 | 0.70 | GAA (0.48) | GAAALOX5MAPTALDH1A1HPGD | |
| SCHEMBL14404161 | 0.70 | ALOX5 (0.48) | GAAALOX5MAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841736-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006077367-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |