Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28106649 | 0.94 | ALDH1A1 (0.41) | ALDH1A1TP53CYP3A4SMN1; SMN2MGLL | |
| SCHEMBL27868051 | 0.91 | SMN1; SMN2 (0.46) | ALDH1A1TP53CYP3A4SMN1; SMN2TDP1 | |
| SCHEMBL204985 | 0.87 | ALDH1A1 (0.44) | ALDH1A1TP53CYP3A4MGLL | |
| SCHEMBL27868048 | 0.85 | SMN1; SMN2 (0.46) | ALDH1A1TP53CYP3A4SMN1; SMN2TDP1 | |
| SCHEMBL8139668 | 0.84 | ALDH1A1 (0.44) | ALDH1A1TP53CYP3A4MGLLTDP1 | |
| SCHEMBL27657798 | 0.83 | ALDH1A1 (0.45) | ALDH1A1TP53CYP3A4MGLL | |
| SCHEMBL2231276 | 0.80 | NAAA (0.42) | ALDH1A1TDP1 | |
| Ammonia Solution, Strong SCHEMBL2404800 | 0.78 | NAAA (0.41) | ALDH1A1 | |
| Butane SCHEMBL441766 | 0.78 | ALDH1A1 (0.44) | ALDH1A1TP53CYP3A4SMN1; SMN2MGLL | |
| SCHEMBL22303945 | 0.77 | MGAM (0.43) | ALDH1A1CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814950-A2 | THERMOPLASTIC WEAR RESISTANT COMPOSITIONS, METHODS OF MANUFACTURE THEREOF AND ARTICLES CONTAINING THE SAME | General Electric Company (US) | 2007-08-08 | — | — | EP | disclosed |
| WO-2007013890-A2 | THERMOPLASTIC WEAR RESISTANT COMPOSITIONS, METHODS OF MANUFACTURE THEREOF AND ARTICLES CONTAINING THE SAME | GENERAL ELECTRIC COMPANY (US) | 2007-02-01 | — | — | WO | disclosed |