SCHEMBL557441

SCHEMBL557441

COc1ccc(C2=CCCCC2)c(OC)c1OC

nearest known ligand 0.52

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PSMB5 P28074 1/20 0.52
PTGS2 P35354 2/20 0.49
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
HPGD P15428 1/20 0.42
HDAC4 P56524 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC8 Q9BY41 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8505494 0.98 PSMB5 (0.51) PSMB5PTGS2KDM4EALDH1A1HPGD
SCHEMBL9380807 0.86 PTGS2 (0.54) PTGS2KDM4EALDH1A1HPGDHDAC4
SCHEMBL12075192 0.79 PSMB5 (0.42) PSMB5PTGS2
SCHEMBL8586239 0.76 PTGS2 (0.48) PSMB5PTGS2KDM4EALDH1A1HPGD
SCHEMBL4918554 0.74 PSMB5 (0.44) PSMB5KDM4EALDH1A1HPGD
SCHEMBL642228 0.73 HDAC4 (0.58) PTGS2KDM4EALDH1A1HPGDHDAC4
SCHEMBL8502139 0.73 KDM4E (0.50) KDM4EALDH1A1HPGDHDAC4HDAC2
SCHEMBL27196492 0.71 PSMB5 (0.42) PSMB5KDM4EALDH1A1HPGD
SCHEMBL29855944 0.71 PSMB5 (0.42) PSMB5KDM4EALDH1A1HPGD
SCHEMBL24028290 0.71 ALDH1A1 (0.50) PSMB5KDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2118269-B1 IN VITRO METHODS FOR THE INDUCTION AND MAINTENANCE OF PLANT CELL LINES AS SINGLE SUSPENSION CELLS WITH INTACT CELL WALLS, AND TRANSFORMATION THEREOF DOW AGROSCIENCES LLC (US) 2013-03-13 EP disclosed
US-8206983-B2 In vitro methods for the induction and maintenance of plant cell lines as single suspension cells with intact cell walls DOW AGROSCIENCES, LLC. (US) 2012-06-26 US disclosed
US-20120034697-A1 IN VITRO METHODS FOR THE INDUCTION AND MAINTENANCE OF PLANT CELL LINES AS SINGLE SUSPENSION CELLS WITH INTACT CELL WALLS, AND TRANSFORMATION THEREOF DOW AGROSCIENCES LLC (US) 2012-02-09 US disclosed
US-8012752-B2 In vitro methods for the induction and maintenance of plant cell lines as single suspension cells with intact cell walls, and transformation thereof DOW AGROSCIENCES LLC (US) 2011-09-06 US disclosed
US-20100159598-A1 In Vitro Methods for the Induction and Maintenance of Plant Cell Lines as Single Suspension Cells With Intact Cell Walls, and Transformation Thereof DOW AGROSCIENCES LLC (US) 2010-06-24 US disclosed
EP-2118269-A2 IN VITRO METHODS FOR THE INDUCTION AND MAINTENANCE OF PLANT CELL LINES AS SINGLE SUSPENSION CELLS WITH INTACT CELL WALLS, AND TRANSFORMATION THEREOF Dow AgroSciences LLC (US) 2009-11-18 EP disclosed
WO-2008083233-A2 IN VITRO METHODS FOR THE INDUCTION AND MAINTENANCE OF PLANT CELL LINES AS SINGLE SUSPENSION CELLS WITH INTACT CELL WALLS, AND TRANSFORMATION THEREOF DOW AGROSCIENCES LLC (US) 2008-07-10 WO disclosed
CN-1036779-C Arylcycloalkane derivatives and their use HOECHST AG (DE) 1997-12-24 CN disclosed