Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | PLAU | P00749 | 1/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.53 |
| ▸ | NOS1 | P29475 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NOS3 | P29474 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16470336 | 0.90 | PLAU (0.64) | MEN1KMT2ATDP1PLAUNOS1 | |
| Hydrochloric Acid SCHEMBL15527609 | 0.89 | NOS1 (0.63) | MEN1KMT2ATDP1PLAUNOS1 | |
| SCHEMBL4104665 | 0.81 | SIGMAR1 (0.71) | KMT2ATDP1NOS1LMNASIGMAR1 | |
| SCHEMBL7881307 | 0.79 | MEN1 (1.00) | MEN1KMT2ATDP1SRD5A2NPC1 | |
| SCHEMBL7881346 | 0.78 | KMT2A (0.79) | MEN1KMT2ATDP1SRD5A2NPC1 | |
| SCHEMBL6855014 | 0.78 | KMT2A (0.79) | MEN1KMT2ATDP1SRD5A2NPC1 | |
| SCHEMBL7696438 | 0.78 | KMT2A (0.79) | MEN1KMT2ATDP1SRD5A2NPC1 | |
| 4-Nitrobenzoic Acid SCHEMBL27900174 | 0.77 | TDP1 (0.88) | MEN1KMT2ATDP1SRD5A2POLB | |
| SCHEMBL8660017 | 0.76 | TDP1 (0.78) | MEN1KMT2ATDP1SRD5A2NPC1 | |
| SCHEMBL7798421 | 0.76 | TDP1 (0.78) | MEN1KMT2ATDP1SRD5A2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7071004-B1 | 14094, a novel human trypsin family member and uses thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2006-07-04 | — | — | US | claimed |
| US-20070009433-A1 | 14094, a novel human trypsin family member and uses thereof | MILLENNIUM PHARMACEUTICALS, INC. | 2007-01-11 | — | — | US | disclosed |
| US-7071004-B1 | 14094, a novel human trypsin family member and uses thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2006-07-04 | — | — | US | disclosed |
| US-20060142187-A1 | Methods for modulating cell-to-cell adhesion using an agonist of C1INH-type protein activity | CBR INSTITUTE FOR BIOMEDICAL RESEARCH, INC. (US) | 2006-06-29 | — | — | US | disclosed |
| WO-2004110356-A2 | METHODS FOR MODULATING CELL-TO-CELL ADHESION USING AN AGONIST OF C1INH-TYPE PROTEIN ACTIVITY | CBR INSTITUTE FOR BIOMEDICAL RESEARCH, INC. (US) | 2004-12-23 | — | — | WO | disclosed |
| WO-1998055130-A1 | EXOSITE ASSAY FOR ANTICOAGULANTS | EMORY UNIVERSITY (US) | 1998-12-10 | — | — | WO | disclosed |