SCHEMBL5574735

SCHEMBL5574735

C[C@H]1C=C2CC(O)(O)C=C[C@]2(C)[C@H]2CC[C@]3(C)CCC[C@H]3[C@H]12

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 3/20 0.39
SHBG P04278 5/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5307661 0.86 CYP19A1 (0.39) CYP19A1SHBG
SCHEMBL5494151 0.76 CYP19A1 (0.48) CYP19A1SHBG
SCHEMBL4318904 0.73 SHBG (0.38) CYP19A1SHBG
SCHEMBL11621787 0.72 SHBG (0.65) SHBG
SCHEMBL11621779 0.72 SHBG (0.65) SHBG
SCHEMBL4304854 0.70 CYP19A1 (0.37) CYP19A1SHBG
SCHEMBL6244374 0.68 SHBG (0.40) CYP19A1SHBG
SCHEMBL6244368 0.68 SHBG (0.37) CYP19A1SHBG
SCHEMBL1418970 0.68 CYP19A1 (0.39) CYP19A1SHBG
SCHEMBL1418971 0.68 CYP19A1 (0.39) CYP19A1SHBG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1807118-A2 STEROID ANALOGS AND CHARACTERIZATION AND TREATMENT METHODS Hollis-Eden Pharmaceuticals Inc. (US) 2007-07-18 EP disclosed
WO-2006110172-A2 STEROID ANALOGS AND CHARACTERIZATION AND TREATMENT METHODS HOLLIS-EDEN PHARMACEUTICALS.INC. (US) 2006-10-19 WO disclosed