Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6695263 | 0.73 | HDAC3 (0.69) | HTTLMNAHPGDHDAC3HDAC4 | |
| SCHEMBL3696138 | 0.71 | MEN1 (0.59) | HTTLMNAHDAC3HDAC4HDAC1 | |
| SCHEMBL14249309 | 0.71 | HDAC3 (0.71) | HTTLMNAHDAC3HDAC4HDAC1 | |
| SCHEMBL10905952 | 0.70 | ALDH1A1 (0.72) | HTTLMNAHPGDKDM4EGAA | |
| Xanthene Carboxylic Acid SCHEMBL30011680 | 0.70 | ATM (0.68) | HTTLMNAHDAC3HDAC4HDAC1 | |
| Xanthene Carboxylic Acid SCHEMBL40617 | 0.70 | ATM (0.68) | HTTLMNAHDAC3HDAC4HDAC1 | |
| SCHEMBL2843958 | 0.69 | HDAC4 (1.00) | HTTLMNAHDAC3HDAC4HDAC1 | |
| Xanthene Carboxylic Acid SCHEMBL2807858 | 0.69 | ATM (0.61) | HTTLMNAHDAC3HDAC4HDAC1 | |
| Xanthene Carboxylic Acid SCHEMBL9551091 | 0.69 | ATM (0.66) | HTTLMNAHDAC3HDAC4HDAC1 | |
| Xanthene Carboxylic Acid SCHEMBL5780275 | 0.69 | ATM (0.66) | HTTLMNAHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070031849-A1 | Three-dimensional structure of DNA recombination/repair protein and use thereof | RIKEN (JP) | 2007-02-08 | — | — | US | disclosed |
| EP-1452590-A1 | STEREOSTRUCTURE OF DNA RECOMBINATION REPAIR ENZYME AND UTILIZATION THEREOF | Riken (JP) | 2004-09-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070031849-A1 | Three-dimensional structure of DNA recombination/repair protein and use thereof | RAD52, RAD50, RAD54L | HTT 3729/4885LMNA 2393/4885HPGD 1291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.