SCHEMBL5575017

SCHEMBL5575017

CC(=O)C(c1ccc(N)cc1)c1ccc(N)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 2/20 0.42
CNR1 P21554 1/20 0.42
MAPT P10636 3/20 0.41
RAB9A P51151 2/20 0.41
NPC1 O15118 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
DHFR P00374 1/20 0.39
TSHR P16473 1/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
CYP19A1 P11511 1/20 0.38
POLB P06746 1/20 0.38
BRD4 O60885 1/20 0.38
SOAT1 P35610 1/20 0.38
CASP6 P55212 1/20 0.37
GFER P55789 1/20 0.37
NOS3 P29474 1/20 0.37
NOS1 P29475 1/20 0.37
NOS2 P35228 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28229481 0.92 THRB (0.52) CNR2CNR1MAPTTDP1TSHR
SCHEMBL6976203 0.90 HDAC3 (0.48) CNR2CNR1MAPTTDP1GFER
SCHEMBL28839218 0.88 MAPT (0.43) CNR2CNR1MAPTRAB9ANPC1
SCHEMBL10791649 0.88 ALDH1A1 (0.52) MAPTRAB9ANPC1SMN1; SMN2TDP1
SCHEMBL7492710 0.84 SLC6A3 (0.44) SMN1; SMN2TSHRALDH1A1HTTLMNA
SCHEMBL28845037 0.84 PTGS1 (0.39) CNR2CNR1MAPTRAB9ANPC1
SCHEMBL28229610 0.81 CA1 (0.38) CNR2CNR1TDP1TSHRBRD4
SCHEMBL17594739 0.81 POLB (0.46) RAB9ANPC1SMN1; SMN2POLBALDH1A1
SCHEMBL4872444 0.81 MAPT (0.41) CNR2MAPTRAB9ANPC1SMN1; SMN2
SCHEMBL15447133 0.81 MAPT (0.41) CNR2CNR1MAPTRAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1790984-B1 A method for producing a biosensor having a covalently bound thin polymeric coat FUJIFILM CORP (JP) 2013-08-28 EP disclosed
EP-1790984-A2 A method for producing a biosensor having a covalently bound thin polymeric coat Fujifilm Corporation (JP) 2007-05-30 EP disclosed