Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PYGL | P06737 | 1/20 | 0.43 |
| ▸ | PPM1D | O15297 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3729801 | 0.83 | HPGD (0.61) | HPGDALDH1A1CYP1A2CYP2C19MAPK1 | |
| SCHEMBL7526213 | 0.77 | CA4 (0.46) | HPGDSMN1; SMN2 | |
| SCHEMBL30264834 | 0.77 | KMT2A (0.48) | HPGDKMT2AROCK2MEN1SMN1; SMN2 | |
| SCHEMBL4234045 | 0.77 | KMT2A (0.48) | HPGDKMT2AROCK2MEN1SMN1; SMN2 | |
| SCHEMBL3732979 | 0.77 | ROCK2 (0.48) | HPGDALDH1A1KMT2AHTTROCK2 | |
| SCHEMBL11480826 | 0.76 | HPGD (0.46) | HPGDALDH1A1GLAKMT2AHTT | |
| SCHEMBL807805 | 0.76 | HPGD (0.51) | HPGDALDH1A1GLAKMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL793710 | 0.75 | HPGD (0.50) | HPGDALDH1A1GLAKMT2AMAPK1 | |
| SCHEMBL5576720 | 0.74 | HTT (0.44) | HPGDTP53ALDH1A1HTTKDM4E | |
| SCHEMBL5573778 | 0.73 | ROCK2 (0.46) | ALDH1A1CYP2C19KMT2AMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070066624-A1 | Chemokine receptor binding compounds | ANORMED, INC. (CA) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066624-A1 | Chemokine receptor binding compounds | CCR5, CCR4, CCR1 | HPGD 1736/4885TP53 2854/4885ALDH1A1 3484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.