Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.44 |
| ▸ | CHRNG | P07510 | 1/20 | 0.44 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.44 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | CHRND | Q07001 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9640678 | 0.84 | GLS (0.48) | SLC6A2CHRNA1CHRNGITGA5CHRNB1 | |
| SCHEMBL3732979 | 0.83 | ROCK2 (0.48) | ROCK2ALDH1A1SMN1; SMN2OGG1GLS | |
| SCHEMBL996782 | 0.81 | HDAC4 (0.44) | ROCK2S1PR1S1PR3 | |
| SCHEMBL5572682 | 0.80 | MAPT (0.49) | SLC6A4ALDH1A1SMN1; SMN2GLSMAPK1 | |
| SCHEMBL4984142 | 0.80 | MAPT (0.49) | SLC6A4ALDH1A1SMN1; SMN2GLSMAPK1 | |
| SCHEMBL4598598 | 0.78 | S1PR3 (0.49) | SLC6A2CHRNA1CHRNGITGA5CHRNB1 | |
| SCHEMBL4234045 | 0.76 | KMT2A (0.48) | ROCK2SMN1; SMN2OGG1MEN1KMT2A | |
| SCHEMBL30264834 | 0.76 | KMT2A (0.48) | ROCK2SMN1; SMN2OGG1MEN1KMT2A | |
| SCHEMBL28830732 | 0.75 | PSEN1 (0.44) | SLC6A2CHRNA1CHRNGITGA5CHRNB1 | |
| SCHEMBL3623486 | 0.75 | MEN1 (0.51) | SLC6A2SLC6A4CYP2C19ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070066624-A1 | Chemokine receptor binding compounds | ANORMED, INC. (CA) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066624-A1 | Chemokine receptor binding compounds | CCR5, CCR4, CCR1 | ROCK2 1733/4885SLC6A2 3893/4885CHRNA1 1133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.