Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 16/20 | 0.43 |
| ▸ | CCR4 | P51679 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4609996 | 0.91 | CCR5 (0.50) | CCR5CCR4KCNH2 | |
| SCHEMBL4610004 | 0.91 | CCR5 (0.50) | CCR5CCR4KCNH2 | |
| SCHEMBL4652438 | 0.88 | CCR5 (0.52) | CCR5CCR4KCNH2HTR6 | |
| SCHEMBL4652432 | 0.88 | CCR5 (0.52) | CCR5CCR4KCNH2HTR6 | |
| SCHEMBL5575401 | 0.87 | CCR5 (0.44) | CCR5CCR4KCNH2DRD2HTR6 | |
| SCHEMBL5572538 | 0.85 | CCR5 (0.41) | CCR5CCR4KCNH2ALDH1A1MAPT | |
| SCHEMBL14571188 | 0.81 | ALDH1A1 (0.40) | CCR5ALDH1A1MAPTHPGDTSHR | |
| SCHEMBL4608051 | 0.80 | CCR5 (0.46) | CCR5CCR4KCNH2MAPT | |
| SCHEMBL4598546 | 0.80 | ALDH1A1 (0.41) | CCR5ALDH1A1MAPTHPGDTSHR | |
| SCHEMBL4597271 | 0.79 | DRD2 (0.45) | CCR5KCNH2DRD2HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070066624-A1 | Chemokine receptor binding compounds | ANORMED, INC. (CA) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066624-A1 | Chemokine receptor binding compounds | CCR5, CCR4, CCR1 | CCR5 1/4885CCR4 2/4885KCNH2 4762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.