SCHEMBL5575751

SCHEMBL5575751

Cc1c(I)cc2ccccc2c1Br

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 5/20 0.41
CYP2A6 P11509 4/20 0.41
POLB P06746 1/20 0.39
TSHR P16473 3/20 0.38
ALDH1A1 P00352 6/20 0.37
HSD17B10 Q99714 5/20 0.37
HIF1A Q16665 2/20 0.37
CYP1B1 Q16678 1/20 0.37
HPGD P15428 3/20 0.36
KDM4E B2RXH2 2/20 0.36
GAA P10253 1/20 0.36
GRIN2D O15399 1/20 0.35
GRIN2A Q12879 1/20 0.35
GRIN2C Q14957 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.34
CYP3A4 P08684 1/20 0.34
MAPK1 P28482 1/20 0.34
CASP1 P29466 1/20 0.34
RAB9A P51151 1/20 0.34
CASP7 P55210 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10883903 0.79 CYP1A2 (0.48) CYP1A2CYP2A6POLBTSHRALDH1A1
SCHEMBL12925915 0.79 ALDH1A1 (0.44) CYP1A2CYP2A6POLBTSHRALDH1A1
SCHEMBL30576383 0.79 CYP1A2 (0.48) CYP1A2CYP2A6POLBTSHRALDH1A1
SCHEMBL19063378 0.76 ALDH1A1 (0.41) CYP1A2CYP2A6POLBTSHRALDH1A1
SCHEMBL28718547 0.76 POLB (0.48) CYP1A2POLBALDH1A1HSD17B10HIF1A
SCHEMBL13601825 0.76 POLB (0.39) CYP1A2CYP2A6POLBTSHRALDH1A1
SCHEMBL19616917 0.76 POLB (0.53) CYP1A2CYP2A6POLBTSHRALDH1A1
SCHEMBL30064932 0.76 POLB (0.53) CYP1A2CYP2A6POLBTSHRALDH1A1
SCHEMBL20180020 0.75 CYP2A6 (0.45) CYP1A2CYP2A6TSHRALDH1A1HSD17B10
SCHEMBL19617285 0.73 ALDH1A1 (0.47) CYP1A2CYP2A6ALDH1A1HSD17B10HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007084373-A2 SEPARATION OF FULLERENE C60 AND C70 USING CRYSTALLIZATION THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2007-07-26 WO disclosed