Sugi Predict

Sugi Predict / Compounds / SCHEMBL5576075

SCHEMBL5576075

SCHEMBL5576075

[c]1ncccc1/C=C/c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP11B1 P15538 1/20 0.48
▸ CYP11B2 P19099 1/20 0.48
▸ MEN1 O00255 2/20 0.42
▸ KMT2A Q03164 2/20 0.42
▸ NFE2L2 Q16236 2/20 0.39
▸ MAOB P27338 3/20 0.39
▸ KDM4E B2RXH2 4/20 0.39
▸ NPC1 O15118 1/20 0.39
▸ LMNA P02545 1/20 0.39
▸ PKM P14618 1/20 0.39
▸ RAB9A P51151 1/20 0.39
▸ GRM5 P41594 1/20 0.39
▸ MAOA P21397 2/20 0.39
▸ CYP19A1 P11511 1/20 0.39
▸ ALDH1A1 P00352 2/20 0.38
▸ HPGD P15428 2/20 0.38
▸ ADRA2A P08913 1/20 0.38
▸ NISCH Q9Y2I1 1/20 0.38
▸ HDAC6 Q9UBN7 2/20 0.38
▸ HDAC3 O15379 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5576077 1.00 CYP11B1 (0.48) CYP11B1CYP11B2MEN1KMT2ANFE2L2
SCHEMBL1200601 0.83 CYP11B1 (0.58) CYP11B1CYP11B2MEN1KMT2ANFE2L2
SCHEMBL3848992 0.72 NFE2L2 (0.52) CYP11B1CYP11B2MEN1KMT2ANFE2L2
SCHEMBL3848997 0.72 NFE2L2 (0.52) CYP11B1CYP11B2MEN1KMT2ANFE2L2
SCHEMBL745255 0.70 — —
(Z)-1,2-Diphenylethene SCHEMBL27619643 0.69 MAOB (0.65) CYP11B1CYP11B2MEN1KMT2ANFE2L2
(Z)-1,2-Diphenylethene SCHEMBL9134305 0.69 MAOB (0.73) CYP11B1CYP11B2MEN1KMT2ANFE2L2
(Z)-1,2-Diphenylethene SCHEMBL443 0.69 MAOB (0.73) CYP11B1CYP11B2MEN1KMT2ANFE2L2
(Z)-1,2-Diphenylethene SCHEMBL22712863 0.69 MAOB (0.73) CYP11B1CYP11B2MEN1KMT2ANFE2L2
(Z)-1,2-Diphenylethene SCHEMBL21847984 0.69 MAOB (0.73) CYP11B1CYP11B2MEN1KMT2ANFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112368143-B Laminate body 住友化学株式会社 2023-08-08 — — CN disclosed
CN-112748490-A Image display device 住友化学株式会社 2021-05-04 — — CN disclosed
CN-112005141-A Polarizing plate 住友化学株式会社 2020-11-27 — — CN disclosed
US-9422286-B2 Metal-binding bifunctional compounds as diagnostic agents for Alzheimer's disease WASHINGTON UNIVERSITY (US) 2016-08-23 — — US disclosed
US-20150209452-A1 METAL-BINDING BIFUNCTIONAL COMPOUNDS AS DIAGNOSTIC AGENTS FOR ALZHEIMER'S DISEASE WASHINGTON UNIVERSITY (US) 2015-07-30 — — US disclosed
US-20070261601-A1 Hardening Composition, Antireflective Film, Method of Producing the Same, Polarizing Plate and Image Display Unit FUJIFILM CORPORATION (JP) 2007-11-15 — — US disclosed
WO-2006033456-A1 HARDENING COMPOSITION, ANTIREFLECTIVE FILM, METHOD OF PRODUCING THE SAME, POLARIZING PLATE AND IMAGE DISPLAY UNIT FUJIFILM CORPORATION (JP) 2006-03-30 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150209452-A1 METAL-BINDING BIFUNCTIONAL COMPOUNDS AS DIAGNOSTIC AGENTS FOR ALZHEIMER'S DISEASE APBA1, PSEN2, PSEN1 CYP11B1 3797/4885CYP11B2 3338/4885MEN1 592/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.