Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.72 |
| ▸ | HTT | P42858 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1915286 | 0.88 | MAPT (0.68) | ALDH1A1HTTMAPTGAAKDM4E | |
| SCHEMBL1915954 | 0.88 | MAPT (0.66) | ALDH1A1HTTMAPTGAAKDM4E | |
| SCHEMBL17899118 | 0.87 | ALDH1A1 (0.74) | ALDH1A1HTTMAPTGAAKDM4E | |
| SCHEMBL6861634 | 0.86 | ALDH1A1 (0.77) | ALDH1A1HTTMAPTGAAKDM4E | |
| SCHEMBL17899112 | 0.86 | ALDH1A1 (0.83) | ALDH1A1HTTMAPTGAAKDM4E | |
| SCHEMBL5574964 | 0.85 | ALDH1A1 (0.71) | ALDH1A1HTTMAPTGAAKDM4E | |
| SCHEMBL5574968 | 0.85 | ALDH1A1 (0.71) | ALDH1A1HTTMAPTGAAKDM4E | |
| SCHEMBL5574960 | 0.85 | ALDH1A1 (0.71) | ALDH1A1HTTMAPTGAAKDM4E | |
| SCHEMBL2396558 | 0.76 | ALDH1A1 (0.60) | ALDH1A1HTTMAPTGAAKDM4E | |
| SCHEMBL2399219 | 0.76 | ALDH1A1 (0.58) | ALDH1A1HTTMAPTGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070031849-A1 | Three-dimensional structure of DNA recombination/repair protein and use thereof | RIKEN (JP) | 2007-02-08 | — | — | US | disclosed |
| EP-1452590-A1 | STEREOSTRUCTURE OF DNA RECOMBINATION REPAIR ENZYME AND UTILIZATION THEREOF | Riken (JP) | 2004-09-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070031849-A1 | Three-dimensional structure of DNA recombination/repair protein and use thereof | RAD52, RAD50, RAD54L | ALDH1A1 1829/4885HTT 3729/4885MAPT 3144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.