Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.83 |
| ▸ | HTT | P42858 | 2/20 | 0.83 |
| ▸ | MAPT | P10636 | 5/20 | 0.72 |
| ▸ | GAA | P10253 | 2/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6861634 | 0.89 | ALDH1A1 (0.77) | ALDH1A1HTTMAPTGAAALOX5 | |
| SCHEMBL17899118 | 0.87 | ALDH1A1 (0.74) | ALDH1A1HTTMAPTGAAPOLB | |
| SCHEMBL5576161 | 0.86 | ALDH1A1 (0.72) | ALDH1A1HTTMAPTGAAPOLB | |
| SCHEMBL1914731 | 0.86 | ALDH1A1 (0.62) | ALDH1A1HTTMAPTGAAPOLB | |
| SCHEMBL1915756 | 0.86 | ALDH1A1 (0.62) | ALDH1A1HTTMAPTGAAPOLB | |
| SCHEMBL5574960 | 0.85 | ALDH1A1 (0.71) | ALDH1A1HTTMAPTGAAPOLB | |
| SCHEMBL5574964 | 0.85 | ALDH1A1 (0.71) | ALDH1A1HTTMAPTGAAPOLB | |
| SCHEMBL5574968 | 0.85 | ALDH1A1 (0.71) | ALDH1A1HTTMAPTGAAPOLB | |
| SCHEMBL6862088 | 0.84 | GAA (1.00) | ALDH1A1HTTMAPTGAAPOLB | |
| SCHEMBL1915349 | 0.77 | ALDH1A1 (0.60) | ALDH1A1HTTMAPTGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10266527-B2 | T-box riboswitch-binding anti-bacterial compounds | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF ALBANY (US) | 2019-04-23 | — | — | US | disclosed |
| US-20160194317-A1 | T-BOX RIBOSWITCH-BINDING ANTI-BACTERIAL COMPOUNDS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2016-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10266527-B2 | T-box riboswitch-binding anti-bacterial compounds | TARBP1, AARS1, NSUN3 | ALDH1A1 3473/4885HTT 1672/4885MAPT 4117/4885 |
| US-20160194317-A1 | T-BOX RIBOSWITCH-BINDING ANTI-BACTERIAL COMPOUNDS | TARBP1, AARS1, NSUN3 | ALDH1A1 3473/4885HTT 1672/4885MAPT 4117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.