Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 5/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.39 |
| ▸ | CDK4 | P11802 | 2/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.39 |
| ▸ | CCND1 | P24385 | 2/20 | 0.39 |
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | CCND3 | P30281 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2951395 | 0.89 | ALOX5 (0.43) | POLBPARP1GAAGFER | |
| SCHEMBL28088109 | 0.84 | APP (0.39) | GAAADORA2AADORA1 | |
| SCHEMBL9429841 | 0.84 | MGAM (0.39) | PARP1SMPD3GAA | |
| SCHEMBL2950385 | 0.84 | BRD4 (0.40) | POLBPARP1GAA | |
| SCHEMBL29148788 | 0.82 | AMY1A (0.43) | NOX1SMPD3GAAGFER | |
| SCHEMBL5576182 | 0.82 | STAT3 (0.51) | NOX1CYP1A1CYP1A2CYP1B1POLB | |
| SCHEMBL31471705 | 0.81 | CDC25A (0.37) | PARP1GAACDK4CCND1 | |
| SCHEMBL29915582 | 0.80 | GABRA1 (0.36) | GAACDK4CCNA2CCND1CDK2 | |
| SCHEMBL8003382 | 0.80 | NPC1 (0.40) | NOX1POLBSMPD3GAAGFER | |
| SCHEMBL28442526 | 0.80 | NPC1 (0.40) | NOX1POLBSMPD3GAAGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4329742-A1 | COMPOSITIONS COMPRISING EPA AND METHODS OF USING THE SAME FOR TREATING AND/OR PREVENTING ENDOTHELIAL DYSFUNCTION IN A SUBJECT | Amarin Pharmaceuticals Ireland Limited (IE) | 2024-03-06 | — | — | EP | disclosed |
| WO-2022232633-A1 | COMPOSITIONS COMPRISING EPA AND METHODS OF USING THE SAME FOR TREATING AND/OR PREVENTING ENDOTHELIAL DYSFUNCTION IN A SUBJECT | AMARIN PHARMACEUTICALS IRELAND LIMITED (IE) | 2022-11-03 | — | — | WO | disclosed |
| US-7291503-B2 | Reversible resistivity-based sensors | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-11-06 | — | — | US | disclosed |
| US-20040235184-A1 | Reversible resistivity-based sensors | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2004-11-25 | — | — | US | disclosed |
| US-6287452-B1 | METAL OXIDE | DUKE UNIVERSITY | 2001-09-11 | — | — | US | disclosed |
| US-5980705-A | DETECTING NITRIC OXIDE HAVING SURFACE REGION FORMED OF METAL WHICH COMPLEXES WITH NITRIC OXIDE WHEN EXPOSED TO FLUID CONTAINING NITRIC OXIDE; IN BIOLOGICAL SAMPLES | DUKE UNIVERSITY (US) | 1999-11-09 | — | — | US | disclosed |