Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | CCR5 | P51681 | 8/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5576380 | 1.00 | HDAC1 (0.45) | HDAC1HDAC8HDAC6CCR5GPR119 | |
| SCHEMBL27726421 | 0.85 | CCR5 (0.40) | CCR5 | |
| SCHEMBL5576650 | 0.80 | CCR5 (0.52) | CCR5GPR119KDM4EPKMTP53 | |
| SCHEMBL4597329 | 0.80 | CCR5 (0.52) | CCR5GPR119KDM4EPKMTP53 | |
| SCHEMBL4598038 | 0.79 | CCR5 (0.45) | CCR5GPR119KDM4EPKMTP53 | |
| SCHEMBL4623933 | 0.79 | CCR5 (0.45) | CCR5GPR119KDM4EPKMTP53 | |
| SCHEMBL4597618 | 0.78 | CCR5 (0.57) | HDAC1HDAC8HDAC6CCR5GPR119 | |
| SCHEMBL5576348 | 0.78 | CCR5 (0.57) | HDAC1HDAC8HDAC6CCR5GPR119 | |
| SCHEMBL5576545 | 0.78 | GPR119 (0.47) | CCR5GPR119KDM4EPKMSTS | |
| SCHEMBL4597797 | 0.78 | GPR119 (0.47) | CCR5GPR119KDM4EPKMSTS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070066624-A1 | Chemokine receptor binding compounds | ANORMED, INC. (CA) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066624-A1 | Chemokine receptor binding compounds | CCR5, CCR4, CCR1 | HDAC1 958/4885HDAC8 1305/4885HDAC6 768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.