Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 12/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 8/20 | 0.56 |
| ▸ | PI4KA | P42356 | 10/20 | 0.51 |
| ▸ | PI4K2B | Q8TCG2 | 10/20 | 0.51 |
| ▸ | PI4K2A | Q9BTU6 | 10/20 | 0.51 |
| ▸ | PI4KB | Q9UBF8 | 10/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.51 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL580610 | 0.75 | ADORA2A (0.64) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL667204 | 0.74 | ADORA2A (0.62) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL28413958 | 0.74 | ADORA2A (0.62) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL2342091 | 0.72 | ADORA2A (0.60) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL106573 | 0.72 | ADORA2A (1.00) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL8284838 | 0.72 | ADORA2A (0.60) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL1357265 | 0.72 | ADORA2A (0.60) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL13007709 | 0.72 | ADORA2A (0.60) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL1370892 | 0.72 | ADORA2A (0.60) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL8069211 | 0.72 | ADORA2A (0.60) | ADORA2AADORA1PI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117568042-A | Soil restoration agent for symbiotic bacteria and algae, and preparation and application methods thereof | 安徽建筑大学 | 2024-02-20 | — | — | CN | disclosed |
| US-20070038380-A1 | Crystal structure of E.coli GDP-fucose synthetase (and complexes thereof) and methods of identifying agonists and antagonists using same | SOMERS WILLIAM S | 2007-02-15 | — | — | US | disclosed |
| US-6459996-B1 | IDENTIFYING A SPECIES WHICH IS AN AGONIST OR ANTAGONIST OF GDP-FUCOSE SYNTHETASE ACTIVITY OR BINDING | AMERICAN HOME PRODUCTS CORPORATION | 2002-10-01 | — | — | US | disclosed |
| EP-1105523-A4 | CRYSTAL STRUCTURE OF ESCHERICHIA COLI GDP-FUCOSE SYNTHETASE AND METHODS OF ITS USE | WYETH CORP (US) | 2002-09-25 | — | — | EP | disclosed |
| EP-1105523-A1 | CRYSTAL STRUCTURE OF ESCHERICHIA COLI GDP-FUCOSE SYNTHETASE AND METHODS OF ITS USE | American Home Products Corporation (US) | 2001-06-13 | — | — | EP | disclosed |
| WO-2000009744-A9 | CRYSTAL STRUCTURE OF ESCHERICHIA COLI GDP-FUCOSE SYNTHETASE AND METHODS OF ITS USE | AMERICAN HOME PROD (US) | 2000-05-25 | — | — | WO | disclosed |
| WO-2000009744-A1 | CRYSTAL STRUCTURE OF ESCHERICHIA COLI GDP-FUCOSE SYNTHETASE AND METHODS OF ITS USE | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-02-24 | — | — | WO | disclosed |